Kinetics of the reversible reaction of papain with 5,5′-dithiobis-(2-nitrobenzoate) dianion: evidence for nucleophilic reactivity in the un-ionized thiol group of cysteine-25 and for general acid catalysis by histidine-159 of the reaction of the 5-mercapto-2-nitrobenzoate dianion with the papain-5-mercapto-2-nitrobenzoate mixed disulphide

G Little; K Brocklehurst

首页> 外文期刊>The biochemical journal >Kinetics of the reversible reaction of papain with 5,5′-dithiobis-(2-nitrobenzoate) dianion: evidence for nucleophilic reactivity in the un-ionized thiol group of cysteine-25 and for general acid catalysis by histidine-159 of the reaction of the 5-mercapto-2-nitrobenzoate dianion with the papain-5-mercapto-2-nitrobenzoate mixed disulphide

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Kinetics of the reversible reaction of papain with 5,5′-dithiobis-(2-nitrobenzoate) dianion: evidence for nucleophilic reactivity in the un-ionized thiol group of cysteine-25 and for general acid catalysis by histidine-159 of the reaction of the 5-mercapto-2-nitrobenzoate dianion with the papain-5-mercapto-2-nitrobenzoate mixed disulphide

机译：用5,5'-dithiobis-（2-硝基苯甲酸酯）豚木材可逆反应的动力学：半胱氨酸-25的未电离硫醇基团中的亲核反应性的证据和通过组氨酸-159的一般酸催化5-巯基-2-硝基苯甲酸乳酸豚，用木瓜 - 5-巯基-2-硝基苯甲酸酯混合二硫化物

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《The biochemical journal》 |1972年第2期|共页
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G Little; K Brocklehurst;
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1. Kinetics of the reversible reaction of papain with 5,5′-dithiobis-(2-nitrobenzoate) dianion: evidence for nucleophilic reactivity in the un-ionized thiol group of cysteine-25 and for general acid catalysis by histidine-159 of the reaction of the 5-mercapto-2-nitrobenzoate dianion with the papain-5-mercapto-2-nitrobenzoate mixed disulphide [J] . G Little, K Brocklehurst The biochemical journal . 1972,第2期

机译：用5,5'-dithiobis-（2-硝基苯甲酸酯）豚木材可逆反应的动力学：半胱氨酸-25的未电离硫醇基团中的亲核反应性的证据和通过组氨酸-159的一般酸催化5-巯基-2-硝基苯甲酸乳酸豚，用木瓜 - 5-巯基-2-硝基苯甲酸酯混合二硫化物
2. Kinetics of the reversible reaction of papain with 5,5′-dithiobis-(2-nitrobenzoate) dianion: evidence for nucleophilic reactivity in the un-ionized thiol group of cysteine-25 and for general acid catalysis by histidine-159 of the reaction of the 5-mercapto-2-nitrobenzoate dianion with the papain-5-mercapto-2-nitrobenzoate mixed disulphide [J] . G Little, K Brocklehurst The biochemical journal . 1972,第2期

机译：用5,5'-dithiobis-（2-硝基苯甲酸酯）豚木材可逆反应的动力学：半胱氨酸-25的未电离硫醇基团中的亲核反应性的证据和通过组氨酸-159的一般酸催化5-巯基-2-硝基苯甲酸乳酸豚，用木瓜 - 5-巯基-2-硝基苯甲酸酯混合二硫化物
3. Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2′- and with 4,4′- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system [J] . G Little, K Brocklehurst The biochemical journal . 1972,第2期

机译：各种质子态的反应性在木瓜蛋白酶和L-半胱氨酸的反应中，用2,2'-二吡啶氨基酯：在半胱氨酸-25残基的未电离硫醇组中的亲核反应性的证据木瓜蛋白酶通过其与组氨酸-159-芦笋-175氢键系统的相互作用
4. Micellar catalysis of the nucleophilic substitution reactions of organophosphorus compounds: Computational and kinetic studies of dicapthon degradation by o-iodosobenzoic acid. [D] . Nardviriyakul, Nahathai. 2000

机译：胶束催化的有机磷化合物的亲核取代反应：邻碘代苯甲酸降解双环酮的计算和动力学研究。
5. Kinetics of the reversible reaction of papain with 55-dithiobis-(2-nitrobenzoate) dianion: evidence for nucleophilic reactivity in the un-ionized thiol group of cysteine-25 and for general acid catalysis by histidine-159 of the reaction of the 5-mercapto-2-nitrobenzoate dianion with the papain-5-mercapto-2-nitrobenzoate mixed disulphide. [O] . G Little, K Brocklehurst 1972

机译：木瓜蛋白酶与55-二硫代双-（2-硝基苯甲酸酯）二价阴离子可逆反应的动力学：半胱氨酸-25未电离硫醇基团中亲核反应性的证据以及组氨酸-159对酸反应的一般酸催化作用将5-巯基-2-硝基苯甲酸酯与木瓜蛋白酶5-巯基-2-硝基苯甲酸酯混合的二硫化物。
6. Kinetics of the reversible reaction of papain with 5,5'-dithiobis-(2-nitrobenzoate) dianion: evidence for nucleophilic reactivity in the un-ionized thiol group of cysteine-25 and for general acid catalysis by histidine-159 of the reaction of the 5-mercapto-2-nitrobenzoate dianion with the papain-5-mercapto-2-nitrobenzoate mixed disulphide. [O] . Little, G, Brocklehurst, K 1972

机译：木瓜蛋白酶与5,5'-二硫代双-（2-硝基苯甲酸酯）二价阴离子可逆反应的动力学：半胱氨酸-25未电离硫醇基团中亲核反应性的证据，以及组氨酸-159对酸反应的一般酸催化作用将5-巯基-2-硝基苯甲酸酯与木瓜蛋白酶5-巯基-2-硝基苯甲酸酯混合的二硫化物。

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