首页> 外文期刊>The biochemical journal >Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2′- and with 4,4′- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system

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Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2′- and with 4,4′- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system

机译：各种质子态的反应性在木瓜蛋白酶和L-半胱氨酸的反应中，用2,2'-二吡啶氨基酯：在半胱氨酸-25残基的未电离硫醇组中的亲核反应性的证据木瓜蛋白酶通过其与组氨酸-159-芦笋-175氢键系统的相互作用

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《The biochemical journal》 |1972年第2期|共页
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G Little; K Brocklehurst;
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1. Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2′- and with 4,4′- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system [J] . G Little, K Brocklehurst The biochemical journal . 1972,第2期

机译：各种质子态的反应性在木瓜蛋白酶和L-半胱氨酸的反应中，用2,2'-二吡啶氨基酯：在半胱氨酸-25残基的未电离硫醇组中的亲核反应性的证据木瓜蛋白酶通过其与组氨酸-159-芦笋-175氢键系统的相互作用
2. Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2′- and with 4,4′- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system [J] . G Little, K Brocklehurst The biochemical journal . 1972,第2期

机译：各种质子态的反应性在木瓜蛋白酶和L-半胱氨酸的反应中，用2,2'-二吡啶氨基酯：在半胱氨酸-25残基的未电离硫醇组中的亲核反应性的证据木瓜蛋白酶通过其与组氨酸-159-芦笋-175氢键系统的相互作用
3. Kinetics of the reversible reaction of papain with 5,5′-dithiobis-(2-nitrobenzoate) dianion: evidence for nucleophilic reactivity in the un-ionized thiol group of cysteine-25 and for general acid catalysis by histidine-159 of the reaction of the 5-mercapto-2-nitrobenzoate dianion with the papain-5-mercapto-2-nitrobenzoate mixed disulphide [J] . G Little, K Brocklehurst The biochemical journal . 1972,第2期

机译：用5,5'-dithiobis-（2-硝基苯甲酸酯）豚木材可逆反应的动力学：半胱氨酸-25的未电离硫醇基团中的亲核反应性的证据和通过组氨酸-159的一般酸催化5-巯基-2-硝基苯甲酸乳酸豚，用木瓜 - 5-巯基-2-硝基苯甲酸酯混合二硫化物
4. Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 22- and with 44- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system. [O] . K Brocklehurst, G Little 1972

机译：木瓜蛋白酶和L-半胱氨酸与22-和44-二吡啶基二硫化物的反应中各种质子状态的反应性：证据表明半胱氨酸-25残基的未电离硫醇基团具有亲核反应性木瓜蛋白酶因其与组氨酸-159-天冬酰胺-175氢键系统的相互作用而引起。
5. Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2'- and with 4,4'- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system. [O] . Brocklehurst, K, Little, G 1972

机译：木瓜蛋白酶和L-半胱氨酸与2,2'-和4,4'-二吡啶基二硫化物的反应中各种质子状态的反应性：证据表明半胱氨酸-25残基的未电离硫醇基团具有亲核反应性木瓜蛋白酶因其与组氨酸-159-天冬酰胺-175氢键系统的相互作用而引起。

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