Benzylation Of Anisole Catalyzed By Mocl_5 Or Mocl_5/molecularsieve System

摘要

MoCl_5 was found as a new catalyst for the benzylation of anisole. In comparison to the general Lewis acid, such as FeCl_3, ZnCl_2, and AlCl_3, the reactivity of MoCl_5 was higher than AlCl_3 but lower than FeCl_3 under the same reaction conditions. When MoCl_5 was supported on HZSM-5 or TS-1 molecular sieve, the yield of this reaction was increased from 45% to 99% or 98%, and the selectivity of paralortho was promoted from 1:1 to 1.9:1 or 2.2:1, respectively. A mechanism of anisole benzylation over MoCl_5 was proposed, which was different from the traditional Friedel-Crafts alkylation mechanism.