...
首页> 外文期刊>Ecotoxicology and Environmental Safety >Application of an algal growth inhibition assay to determine distribution coefficients of benzalkonium ions between kaolinite and water
【24h】

Application of an algal growth inhibition assay to determine distribution coefficients of benzalkonium ions between kaolinite and water

机译:藻类生长抑制测定法测定高岭土与水中苯并烷基离子分布系数的应用

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       

摘要

Benzalkonium compounds are widely used and found in environmental samples. Due to their amphiphilic nature, it is important to know sorption coefficients to account their bioavailability. However, currently available models describing their partitioning were developed using low molecular weight homologues and it cannot be ascertained whether they are applicable to their higher molecular weight homologues. Reasons for the scarcity of data on highly sorptive compounds include the lack of reliable quantification techniques for analyzing these chemicals at environmentally relevant levels. This study, therefore, reports on an algal growth inhibition assay-based method for the determination of kaolinite/water distribution coefficients for benzalkonium compounds at their environmentally relevant concentration range. Sorption to clay was computed using the difference between median effective concentration determined in a culture with kaolinite and that derived from a culture grown in standard medium. A kinetic model was used to account for uptake into algal cells and to calculate free concentrations. Due to the sensitivity of the algal species, Pseudokirchneriella subcapitata, it was possible to determine distribution coefficients below micromole per liter concentrations. The computed distribution coefficients showed a linear increase with number of carbon atoms in the alkyl chain up to 14. The proposed bioassay-based method should be applicable to determine distribution coefficients for highly hydrophobic chemicals and ionic liquids at a concentration range lower than typical analytical limits.
机译:苯扎尼铵化合物广泛使用并在环境样品中发现。由于它们的两亲性质,了解吸附系数来估计其生物利用度是重要的。然而,目前使用低分子量同源物开发了描述其分区的现有模型,并且不能确定它们是否适用于其更高的分子量同源物。高吸附化合物数据稀缺的原因包括缺乏可靠的定量技术,用于在环境相关水平下分析这些化学品。因此,该研究报告了藻类生长抑制测定法测定苯扎尼型化合物在其环境相关浓度范围内测定高岭石/水分配系数的方法。使用具有高岭石的培养物中测定的中值有效浓度的差异来计算对粘土的吸附,并衍生自标准介质中生长的培养物。用于将动力学模型用于吸收到藻类细胞并计算自由浓度。由于藻类物种的敏感性,Pseudokirchneriella subcapitata,可以确定每升微仪低于微孔的分布系数。计算的分布系数显示烷基链中的碳原子数的线性增加,最多可达14.所提出的基于生物测定法的方法应适用于测定高度疏水化学品和离子液体的分布系数,其浓度范围低于典型的分析限制。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号