Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus

A. J. McKnight; A. M. Woodman; M. Parkkonen; C. C. Patterson; D. A. Savage; C. Forsblom; K. A. Pettigrew; D. Sadlier; P. H. Groop; A. P. Maxwell

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Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus

机译：1型糖尿病患者SMAD基因DNA多态性与糖尿病肾病遗传易感性的关系

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Aims/hypothesis SMAD proteins are involved in multiple signalling pathways and are key modulators of gene expression. We hypothesised that genetic variation in selected SMAD genes contributes to susceptibility to diabetic nephropathy.

机译：目的/假设SMAD蛋白参与多种信号传导途径，并且是基因表达的关键调节剂。我们假设选定的SMAD基因的遗传变异有助于糖尿病性肾病的易感性。

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《Diabetologia》 |2009年第5期|p.844-849|共6页
作者
A. J. McKnight; A. M. Woodman; M. Parkkonen; C. C. Patterson; D. A. Savage; C. Forsblom; K. A. Pettigrew; D. Sadlier; P. H. Groop; A. P. Maxwell;
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正文语种 eng
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关键词
Association; Genetic predisposition; Polymorphism; SMAD; Susceptibility gene;

机译：协会;遗传易感性;多态性;SMAD;易感基因;

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1. Investigation of Adducin 2 (beta) DNA polymorphisms in genetic predisposition to diabetic nephropathy in Type 1 diabetes. [J] . Currie D, Maxwell AP, Sadlier D, Diabetic medicine: A journal of the British Diabetic Association . 2008,第8期

机译：在1型糖尿病的糖尿病性肾病遗传易感性中研究Adducin 2（beta）DNA多态性。
2. Investigation of Adducin 2 (beta) DNA polymorphisms in genetic predisposition to diabetic nephropathy in Type 1 diabetes. [J] . Currie D, Maxwell AP, Sadlier D, Diabetic medicine: A journal of the British Diabetic Association . 2008,第8期

机译：在1型糖尿病的糖尿病性肾病遗传易感性中研究Adducin 2（beta）DNA多态性。
3. Polymorphism of the angiotensinogen gene and genetic predisposition to diabetic nephropathy in diabetes mellitus type 1 [J] . Chistyakov D.A., Turakulov R.I., Kondratev Ya.Yu., Молекулярная биология . 1999,第2期

机译：1型糖尿病患者血管紧张素原基因多态性与遗传性易感性
4. ACE gene I/D polymorphism and obesity in patients with type 2 diabetes mellitus [C] . Sounira Mehri, Mohamed Hammami International Conference on Engineering MIS . 2017

机译：2型糖尿病患者ACE基因I / D多态性与肥胖
5. Pomen izbranih genskih polimorfizmov pri nastanku diabeti?ne ledvi?ne bolezni pri bolnikih s sladkorno boleznijo tipa 2 =Role of selected gene polymorphisms in the development of diabetic kidney disease in patients with type 2 diabetes mellitus [D] . Seruga, Maja. 2018

机译：选定的遗传多态性在糖尿病肾脏发生中的意义 - 糖尿病患者患者2 =糖尿病肾脏疾病中选定基因多态性的卷和2型糖尿病患者
6. TLR4 Polymorphisms (896AG and 1196CT) Affect the Predisposition to Diabetic Nephropathy in Type 2 Diabetes Mellitus [O] . Narges Khaghanzadeh, Nadereh Naderi, Nazanin Pournasrollah, 2020

机译：TLR4多态性（896A G和1196C T）影响2型糖尿病的糖尿病肾病易感性。
7. Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus [O] . McKnight, A. J., Woodman, A. M., Parkkonen, M., 2009

机译：1型糖尿病患者SMAD基因DNA多态性与糖尿病肾病遗传易感性的关系

Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus

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