机译:褪黑素受体MTNR1B附近的常见遗传变异导致印度亚裔和欧洲白种人中血浆葡萄糖升高和2型糖尿病风险增加
John C. Chambers,1 Weihua Zhang,1 Delilah Zabaneh,1 Joban Sehmi,2 Piyush Jain,2 Mark I. McCarthy,3 Philippe Froguel,4,5 Aimo Ruokonen,6 David Balding,1 Marjo-Riitta Jarvelin,1,7 James Scott,2 Paul Elliott,1 and Jaspal S. Kooner2From the 1 Department of Epidemiology and Publie Health. Imperial College London. London, U.K., the 2 National Heart and Lung Institute, Imperial College London, London, U.K., the 3 Oxford Centre for Diabetes. Endocrinology and Metabolism and Oxford National Institute for Health Research, Biomedical Research Centre, Oxford, U.K., the 4 Section of Genomic Medicine, Imperial College London, London, U.K., and the Centre National de la Recherche Scientifique, 8090-Institute of Biology, Pasteur Institute, Lille, France: the 5 UMR 8090-Institute of Biology, Pasteur Institute, Lille, Prance, the 6 Department of Clinical Sciences/Clinical Chemistry, University Hospital Oulu, Onlu, Finland, and the 7 Institute of Health Sciences and Biocenter Oulu, University of Oulu, Oulu, Finland, and Department of Child and Adolescent Health, National Institute of Health and Welfare, Helsinki, Finland.Corresponding author: Jaspal S. Kooner, j.kooner@imperial.ac.uk.Received 20 December 2008 and accepted 13 July 2009. Published ahead of print at http://diabetes.diabetesjournals.org on 13 August 2009. DOI: 10:2337/db08-1805.© 2009 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativeconmions.org/hcenses/by-nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 17th solely to indicate this fact.,;
机译:褪黑素受体MTNR1B附近的常见遗传变异导致印度亚裔和欧洲白种人中血浆葡萄糖升高和2型糖尿病风险增加
机译:MTNR1B附近的常见遗传变异导致印度人血浆葡萄糖升高和2型糖尿病的风险增加
机译:MTNR1B的常见变体编码褪黑激素受体1B,与2型糖尿病和汉族人空腹血糖相关
机译:使用常见和罕见遗传变异进行风险预测:应用于2型糖尿病
机译:在高加索人和非裔美国人中识别导致2型糖尿病易感性的基因。
机译:褪黑素受体MTNR1B附近的常见遗传变异导致印度亚裔和欧洲白种人中血浆葡萄糖升高和2型糖尿病风险增加
机译:褪黑素受体MTNR1B附近的常见遗传变异导致印度亚裔和欧洲白种人中血浆葡萄糖升高和2型糖尿病风险增加。