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首页> 外文期刊>Diabetes >Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men
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Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men

机译:5327名非糖尿病芬兰男性中18个2型糖尿病易感基因座与胰岛素释放,胰岛素原转化和胰岛素敏感性指标的关联

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摘要

We investigated the effects of 18 confirmed type 2 diabetes risk single nucleotide polymorphisms (SNPs) on insulin sensitivity, insulin secretion, and conversion of proinsulin to insulin.
机译:我们调查了18种确诊的2型糖尿病风险单核苷酸多态性(SNP)对胰岛素敏感性,胰岛素分泌以及胰岛素原向胰岛素转化的影响。

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  • 来源
    《Diabetes》 |2009年第9期|p.2129-2136|共8页
  • 作者单位

    Alena Stancáková,1 Teemu Kuulasmaa,1 Jussi Paananen,1 Anne U. Jackson,2 Lori L. Bonnycastle,3 Francis S. Collins,3 Michael Boehnke,2 Johanna Kuusisto,1 and Markku Laakso1From the 1 Department of Medicine, University of Kuopio and Kuopio University Hospital, Kuopio, Finland, the 2 Center for Statistical Genetics, Department, of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, and the 3 National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.Corresponding author: Markku Laakso. markku.laakso@kuh.fi.Received 27 January 2009 and accepted 27 May 2009.Published ahead of print at http://diabetes.diabetesjournals.org on 5 June 2009. DOI: 10.2337/db09-0117.© 2009 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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