机译:PKCε的缺失通过增加小鼠β-细胞的脂解作用选择性地增强了葡萄糖刺激的胰岛素分泌的放大途径。
James Cantley,1 James G. Burchfield,1,2 Gemma L. Pearson,1 Carsten Schmitz-Peiffer,1,2 Michael Leitges,3 and Trevor J. Biden1,2From the 1 Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia, 2 St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Darlinghurst, New South Wales, Austratia, and the 3 Biotechnology Centre of Oslo, University of Oslo. Oslo, Norway.Corresponding author Trevor Biden, t.biden@garvan.org.au.Received 29 January 2009 and accepted 24 April 2009.Published ahead of print at httpy/diabetes.diabetesjouniaLs.org on 28 April 2009. DOI: 10.2337/db09-0132.© 2009 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativeconunons.org/Ucenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicale this faci.,;
机译:PKCe的删除选择性地通过增加小鼠β细胞的脂解作用来增强葡萄糖刺激的胰岛素分泌的放大途径。
机译:微生物的酚类代谢产物可通过ERK和PKC途径改善葡萄糖刺激的胰岛素分泌,并保护胰岛β细胞免受叔丁基氢过氧化物诱导的毒性
机译:白介素6增强了胰岛β细胞的葡萄糖刺激的胰岛素分泌:PLC-IP ^ sub 3 ^依赖途径的潜在参与。
机译:形成的细胞团调节葡萄糖刺激的胰岛素基因表达并促进胰腺β细胞中胰岛素的分泌
机译:丙酮酸循环途径和胰岛β细胞中葡萄糖刺激的胰岛素分泌
机译:PKCε的删除选择性地通过增加小鼠β细胞的脂解作用来增强葡萄糖刺激的胰岛素分泌的放大途径。
机译:PKC的缺失通过增加小鼠细胞中的脂解作用选择性地增强了葡萄糖刺激的胰岛素分泌的放大途径