机译:蛋白质-酪氨酸磷酸酶1B(PTP1B)的肝脏特异性删除改善代谢综合征,并减轻饮食引起的内质网应激
Mirela Delibegovic,1,6 Derek Zimmer,2 Caitlin Kauffman,2 Kimberly Rak,2 Eun-Gyoung Hong,3,4 You-Ree Cho,4 Jason K. Kim,3,4 Barbara B. Kahn,5 Benjamin G. Neel,1,7 and Kendra K. Bence2From the 'Cancer Biology Program, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, the department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, the 3Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, the 4Department of Internal Medicine, Section of Endocrinology and Metabolism, Yale University School of Medicine, New Haven, Connecticut, the sDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, the "School of Biological Sciences, University of Aberdeen, Aberdeen, U.K., and the 7Division of Stem Cell and Developmental Biology, Ontario Cancer Institute, Toronto, CanadaCorresponding authors: Kendra Bence, kbence@vet.upenn.edu, and Mírela Delibegovic, m.deUbegovic@abdn.ac.uk.Received 9 July 2008 and accepted 8 December 2008.Published ahead of print at http://diabetes.diabetesjournals.org on 15 December 2008. DOI: 10.2337/db08-0913.? 2009 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/Ucenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.,;
机译:肝脏蛋白酪氨酸磷酸酶(PTP)1B的缺失可改善肥胖症和药理作用引起的内质网应激。
机译:肝蛋白酪氨酸磷酸酶(PTP)1B的缺失可改善肥胖和药理作用引起的内质网应激
机译:缺失蛋白质酪氨酸磷酸酶1B通过调节自噬剥离内质网胁迫诱导的心肌功能障碍
机译:由间歇性低氧引起的脑损伤对内质网胁迫,活化剂P66SHC和NADPH氧化酶进行衰减,CYCPU86017-RS化合物衰减
机译:蛋白质酪氨酸磷酸酶1B和内质网应激在肥胖诱导的胰岛素抵抗中的作用。
机译:蛋白质-酪氨酸磷酸酶1B(PTP1B)的肝脏特异性删除改善代谢综合征并减轻饮食引起的内质网应激
机译:蛋白质-酪氨酸磷酸酶1B(PTP1B)的肝脏特异性删除改善代谢综合征,并减轻饮食引起的内质网应激