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Sleep Restriction for 1 Week Reduces Insulin Sensitivity in Healthy Men

机译：限制睡眠1周可降低健康男性的胰岛素敏感性

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摘要

Short sleep duration is associated with impaired glucose tolerance and an increased risk of diabetes. The effects of sleep restriction on insulin sensitivity have not been established. This study tests the hypothesis that decreasing nighttime sleep duration reduces insulin sensitivity and assesses the effects of a drug, modafinil, that increases alertness during wakefulness.
机译：睡眠时间短与葡萄糖耐量降低和糖尿病风险增加有关。睡眠限制对胰岛素敏感性的影响尚未确定。这项研究检验了以下假设：减少夜间睡眠时间会降低胰岛素敏感性，并评估一种药物莫达非尼的作用，该药物可提高清醒时的警觉性。

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  • 来源
    《Diabetes》 |2010年第9期|p.2126-2133|共8页
  • 作者

    Orfeu M Buxton Milena Pavlova Emily W Reid Wei Wang Donald C Simonson Gail K Adler;

  • 作者单位

    Orfeu M. Buxton,1,2 Milena Pavlova,2,3 Emily W. Reid,1 Wei Wang,1,2 Donald C. Simonson,1,2 and Gail K. Adler1,2From the 1 Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, 2 Harvard Medical School, boston, Massachusetts, and the 3 Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts.Corresponding author: Orfeu M. Buxton, orfeu_buxton@hm.s.harvard.edu.Received 11 May 2009 and accepted 18 June 2010. Published ahead of print at http://diabetes.diabetesjournals.org on 28 June 2010. DOI: 10.2337/db09-0699. Clinical trial reg. no. NCT00895570, clinicalnials.gov.© 2010 by the American Diabetes Association. Readers may ase this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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  • 入库时间 2022-08-17 13:45:42

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