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首页> 外文期刊>Diabetes >Local Non-Esterified Fatty Acids Correlate With Inflammation in Atheroma Plaques of Patients With Type 2 Diabetes
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Local Non-Esterified Fatty Acids Correlate With Inflammation in Atheroma Plaques of Patients With Type 2 Diabetes

机译：2型糖尿病患者粥样斑块中局部非酯化脂肪酸与炎症相关

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摘要

Atherosclerosis is prevalent in diabetic patients, but there is little information on the localization of nonesterified fatty acids (NEFAs) within the plaque and their relationship with inflammation. We sought to characterize the NEFA composition and location in human diabetic atheroma plaques by metabolomic analysis and imaging and to address their relationship with inflammation activity.
机译：动脉粥样硬化在糖尿病患者中很普遍，但是关于斑块内非酯化脂肪酸（NEFA）的定位及其与炎症的关系的信息很少。我们试图通过代谢组学分析和成像来表征人糖尿病性动脉粥样斑块中NEFA的组成和位置，并探讨它们与炎症活性的关系。

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  • 来源
    《Diabetes》 |2010年第6期|p.1292-1301|共10页
  • 作者

    Sebastián Mas Roxana Martínez-Pinna Jose Luis Martín-Ventura Raul Pérez Dulcenombre Gomez-Garre Alberto Ortiz Arturo Fernandez-Cruz Fernando Vivanco Jesús Egido;

  • 作者单位

    Sebastián Mas,1 Roxana Martinez-Pinna,1 Jose Luis Martin- Ventura, ' Raul Pérez,2Dulcenombre Gomez-Garre,3 Alberto Ortiz,1 Arturo Fernandez-Cruz,3 Fernando Vivanco,4 andJesús Egido1From the 1 Vascular Pathology and Experimental Nephrology Laboratory, Fundación Jiménez Diaz/Autonoma University/IRSIN, Madrid, Spain, -Nanotechnoiogy Platform, Barcelona Scientific Park, Barcelona, Spain, the 3 Internal Medicine Department, Hospital Clínico San Carlos, Madrid, Spain, and the 4Inmunology Department, Fundación Jiménez Díaz, Madrid, Spain.Corresponding author: Sebastián Mas, smas@fjd.es.Received 10 June 2009 and accepted 18 February 2010. Published ahead of print at http://diabetes.diabetesjournals.org on 3 March 2010. DOI: 10.2337/db09-0848.F 2010 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creatlvecommons.org/licenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. Tliis article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C.. Section 1734 solely Io indicate this fact.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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  • 正文语种 eng
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