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Insulin-Sensitizing Therapy Attenuates Type 2 Diabetes-Mediated Mammary Tumor Progression

机译：胰岛素敏感疗法可减轻2型糖尿病介导的乳腺肿瘤进展

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摘要

Type 2 diabetes increases breast cancer risk and mortality, and hyperinsulinemia has been identified as a major factor linking these two diseases. Thus, we hypothesized that pharmacological reduction of elevated insulin levels would attenuate type 2 diabetes-mediated mammary tumor progression.
机译：2型糖尿病会增加患乳腺癌的风险和死亡率，而高胰岛素血症已被认为是连接这两种疾病的主要因素。因此，我们假设升高胰岛素水平的药理学降低将减弱2型糖尿病介导的乳腺肿瘤的进展。

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  • 来源
    《Diabetes》 |2010年第3期|p.686-693|共8页
  • 作者

    Yvonne Fierz Ruslan Novosyadlyy Archana Vijayakumar Shoshana Yakar Derek LeRoith;

  • 作者单位

    From the Division of Endocrinology, Diabetes and Bone Diseases, The Samuel Bronfman Department of Medicine, Mount Sinai School of Medicine. New York, New York.Corresponding author: Derek LeRoith, derek.leroith@mssm.edu.Received 31 August 2009 and accepted 13 November 2009. Published ahead of print at http://diabetes.diabetesjournals.org on 3 December 2009. DOI: 10.2337/db09-1291.© 2010 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and tlie work is not altered. See http://creativecommons.org/licenses/by -nc-nd/3.0/ for details.The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "adverstisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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  • 入库时间 2022-08-17 13:45:38

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