Efficacy of Metreleptin in Obese Patients With Type 2 Diabetes: Cellular and Molecular Pathways Underlying Leptin Tolerance

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• 来源
  《Diabetes》 |2011年第6期|p.1647-1656|共10页
• 作者

  Hyun-Seuk Moon Giuseppe Matarese Aoife M Brennan John P Chamberland Xiaowen Liu Christina G Fiorenza Geetha H Mylvaganam Luisa Abanni Fortunata Carbone Catherine J Williams Alex M De Paoli Benjamin E Schneider Christos S Mantzoros;

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• 作者单位

  Hytin-Seuk Moon/ Giuseppe Matarese,2 Aoife M. Brennan,1 John P. Chamberland,1 Xiaowen Liu,1 Christina G. Fiorenza,1 Geetha H. Mylvaganam,1 Luisa Abanni,2 Fortunata Carbone,2 Catherine J. Williams,1 Alex M. De Paoli,3 Benjamin E. Schneider,4 and Christos S. Mantzoros1'5Prom the 'Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, the 2Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Conisglio Nazionale delle Ricerche c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Universit? di Napoli Federico II, Napoli, Italy, 3Amgen, Inc., Thousand Oaks, California, the 4Division of Minimally Invasive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, and the ^Section of Endocrinology, Boston VA Healthcare System, Harvard Medical School, Boston, Massachusetts.Corresponding author: Christos S. Mantzoros, cmantzor@bidmc.liarvard.edu.Received 28 December 2010 and accepted 16 March 2011.DOI: 10.2337/dbl0-l?91. Clinical trial reg. no. NCT01275053, clinicaltrials.gov.This article contains Supplementary Data online at http://diabetes, diabetesjournals.org/lookup/suppl/doi:10.2337/dbl0-1791/VDCl.The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Center for Research Resources or the National Institutes of Health.© 2011 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecortunons.org/license&'by -nc-nd/3.0/ for details.,;

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• 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
• 原文格式 PDF
• 正文语种 eng
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• 入库时间 2022-08-17 13:45:35