首页> 外文期刊>Diabetes >Phosphatidylinositol-4-Phosphate-5-Kinase [alpha] Deficiency Alters Dynamics of Glucose-Stimulated Insulin Release to Improve Glucohomeostasis and Decrease Obesity in Mice
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Phosphatidylinositol-4-Phosphate-5-Kinase [alpha] Deficiency Alters Dynamics of Glucose-Stimulated Insulin Release to Improve Glucohomeostasis and Decrease Obesity in Mice

机译:磷酸肌醇4-磷酸5-激酶α缺乏症改变了葡萄糖刺激的胰岛素释放的动力学,从而改善了小鼠的糖稳态和减少肥胖症。

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  • 来源
    《Diabetes》 |2011年第2期|p.454-463|共10页
  • 作者单位

    Ping Huang,1,2 Oladapo Yeku,1,3,4 Haihong Zong,2 Phyllis Tsang,1,2 Wenjuan Su,1,3 Xiao Yu,1,2Shuzhi Teng,6 Mary Osisami,1,5 Yasunori Kanaho,7 Jeffrey E. Pessin,2 and Michael A. Frohman1,2,3,5From the 1 Center for Developmental Genetics, Stony Brook University, Stony Brook, New York, the 2 Department of Phannacology, Stony Brook University, Stony Brook, New York, the 3 Program in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, New York, the 4Medical Scientist Training Program, Stony Brook University, Stony Brook, New York, the "Program in Genetics, Stony Brook University, Stony Brook, New York, the Department of Medical, Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, and the 7 Department of Physiological Chemistry, Graduate School of Comprehensive Human Sciences and Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Japan.Corresponding author: Michael A. Frohman, michael@phanii.stonybrook.edu.Received 28 April 2010 and accepted 10 November 2010.DOI: 10.2337/db 10-0614This article contains Supplementary Data online at http://diabetes. diabetesjoumals.org/lookup/suppl/doi:10.2337/dbl()-0614/-/DCl.P.H. and O.Y. contributed equally to this work.P.H. is currendy affiliated with lhe Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.H.Z. and J. E. P. are currently affiliated with the Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York.X. Y. is currently affiliated with the Department of Biochemistry. Indiana University, Blooming! on, Indiana.© 2011 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, die use is educational and not for profit, and the work is not altered. See http://creativeeommon.s.org/licenses/by -nc-nd/3.0/ for details.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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  • 正文语种 eng
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  • 入库时间 2022-08-17 13:45:34

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