机译:磷酸肌醇4-磷酸5-激酶α缺乏症改变了葡萄糖刺激的胰岛素释放的动力学,从而改善了小鼠的糖稳态和减少肥胖症。
Ping Huang,1,2 Oladapo Yeku,1,3,4 Haihong Zong,2 Phyllis Tsang,1,2 Wenjuan Su,1,3 Xiao Yu,1,2Shuzhi Teng,6 Mary Osisami,1,5 Yasunori Kanaho,7 Jeffrey E. Pessin,2 and Michael A. Frohman1,2,3,5From the 1 Center for Developmental Genetics, Stony Brook University, Stony Brook, New York, the 2 Department of Phannacology, Stony Brook University, Stony Brook, New York, the 3 Program in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, New York, the 4Medical Scientist Training Program, Stony Brook University, Stony Brook, New York, the "Program in Genetics, Stony Brook University, Stony Brook, New York, the Department of Medical, Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, and the 7 Department of Physiological Chemistry, Graduate School of Comprehensive Human Sciences and Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Japan.Corresponding author: Michael A. Frohman, michael@phanii.stonybrook.edu.Received 28 April 2010 and accepted 10 November 2010.DOI: 10.2337/db 10-0614This article contains Supplementary Data online at http://diabetes. diabetesjoumals.org/lookup/suppl/doi:10.2337/dbl()-0614/-/DCl.P.H. and O.Y. contributed equally to this work.P.H. is currendy affiliated with lhe Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.H.Z. and J. E. P. are currently affiliated with the Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York.X. Y. is currently affiliated with the Department of Biochemistry. Indiana University, Blooming! on, Indiana.© 2011 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, die use is educational and not for profit, and the work is not altered. See http://creativeeommon.s.org/licenses/by -nc-nd/3.0/ for details.,;
机译:磷脂酰肌醇-4-磷酸5-激酶α缺乏症改变葡萄糖刺激的胰岛素释放的动力学,以改善小鼠体内的糖稳态和肥胖症。
机译:删除Neuromedin B受体的小鼠表现出口服葡萄糖刺激的胰岛素释放减少
机译:托吡酯可改善高血糖症,并改善ZDF大鼠和db / db小鼠的葡萄糖刺激的胰岛素释放。
机译:饮食诱导的肥胖改变骨重塑,导致小鼠股骨指骨骨质减少
机译:磷脂酶D2在高尔基体结构维持,囊泡运输和葡萄糖刺激的胰岛素释放中的作用以及功能性β细胞质量定量的新型非侵入性方法的验证。
机译:磷脂酰肌醇-4-磷酸5-激酶α缺乏症改变葡萄糖刺激的胰岛素释放的动力学以改善小鼠体内的糖稳态和肥胖症。
机译:磷脂酰肌醇-4-磷酸5-激酶α缺乏症改变葡萄糖刺激的胰岛素释放的动力学,以改善小鼠的糖稳态和减少肥胖。