Bees Klebsiellosis: Key Aspects of Pathogenesis

摘要

Beekeeping is an important part of the several farming sectors’ contemporaneous development in many countries. Bee colonies act not only as food crops’ pollinators, but also provide the population with food, medical and vitamin-stimulating agents. Significant factors that hinder the beekeeping development, along with the cumulative effect of other exogenous and endogenous elements, are infectious pathologies. One of such pathologies is bee colonies’ Klebsiellosis – a factorial, stationary bacterial disease caused by pathogens belonging to the species Klebsiella Pneumoniae and Klebsiella Aerogenes. Such dysbiosis is characterized by apathy, anorexia, dyspeptic symptom complex, intoxication and high mortality in adult bees and their larvae. The lack of justification for this pathology’s development mechanisms became a prerequisite for the formation of bacterial infection’s pathogenetic picture, taking into account the peculiarities of the bee organism’s physiological and morphological structure. Summarizing the latest achievements in clinical and laboratory studies of this pathology both in humane and veterinary medicine, we interpret the main pathogenetic factors of pathogens’ influence on different levels of bee organism’s organization – from the midgut’s wall morphological composition to self-poisoning of the whole macroorganism. The pathogenetic picture formation of this pathological state can contribute to the therapeutic agents’ development in biomedical and veterinary laboratories.