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Bronchoscopic diagnosis and treatment of endobronchial carcinoid: case report and review of the literature

机译:支气管镜诊断和治疗胚胎类癌:案例报告和文学审查

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Carcinoid tumours are rare neuroendocrine neoplasms that mostly occur in younger adults with low tendencies to metastasise. Based on their histological characteristics, they are divided into typical and atypical subtypes. The most common presenting symptoms are due to central airway obstruction. The first step in the diagnostic assessment should be a computed tomography (CT) scan, as it provides information both for local tumour extent and lymph node involvement. Bronchoscopy is the main tool for histological confirmation, evaluation of bronchial wall invasion and removal of endobronchial manifestation with subsequent resolution of atelectasis. Endobronchial ultrasound may be necessary to rule out lymph node metastasis. Somatostatin receptor scintigraphy in combination with CT can rule out further metastatic disease. Surgical resection using parenchyma-sparing techniques remains the gold standard for treatment. For selected patients, endobronchial therapy could be an alternative for minimal invasiveness. Long-term follow-up is suggested due to the high likelihood of recurrence. Here, we describe our clinical experience in a 35-year-old male patient who originally presented with haemoptysis and a central polypoid tumour in the left main bronchus revealed by a CT scan. The histological characteristics were indicative of a typical carcinoid. The patient was treated using an endobronchial approach only. No complications and no recurrences have been observed in a follow-up of 2?years.
机译:类癌肿瘤是罕见的神经内分泌肿瘤,大多出现在具有低倾向转移的年轻成年人中。基于它们的组织学特征,它们分为典型和非典型亚型。最常见的呈现症状是由于中央气道阻塞。诊断评估的第一步应该是计算断层扫描(CT)扫描,因为它提供了局部肿瘤程度和淋巴结受累的信息。支气管镜检查是组织学确认,支气管壁侵袭和去除内核表现的主要工具,随后分辨于Atelectasis。可以在排除淋巴结转移的情况下可能需要胚胎超声。生长抑素受体闪烁与CT组合可以排除进一步转移性疾病。使用实质备用技术进行手术切除仍然是治疗的金标准。对于选定的患者,胚胎治疗可能是最小侵袭性的替代方案。由于复发的可能性很高,建议了长期随访。在这里,我们描述了我们在一名35岁的男性患者中描述的临床经验,这些患者最初呈现出血肿和中央息肉肿瘤,在左主支气管中通过CT扫描显示。组织学特征指示典型的类癌。患者仅使用内核途径处理。在2年的后续行动中没有观察到任何并发症,没有复发。

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