To evaluate the effect of dance on vascular-related factors and cerebral hemodynamics in elderly individuals in Qinghai-Tibetan plateau regions (mean altitude ≥2,300 m). Thirty elderly individuals, who practiced traditional Tibetan Guozhuang dance or did not, were enrolled, respectively. Serum PGC-1α, HCY, FSTL-1, VEGF and HIF-1α were measured by ELISA assays. Carotid artery stenosis and plaque, IMT, extracranial internal carotid artery stenosis and cerebral arteriosclerosis were evaluated using CUS and TCD. Body weight, BMI, heart rate, systolic pressure, and diastolic pressure, serum BGS, TC, LDL, HIF-1α, VEGF, and HCY in the dance group were significantly lower than the no-dance group. FSTL-1 levels, SO 2 and SO 2 /heart rate ratio in the dance group were significantly higher than the no-dance group. Incidence of extracranial internal carotid artery stenosis, carotid stenosis and plaque in the dance group was significantly lower than the no-dance group. IMT was a significant positive correlation between PGC-1α and HCY in the no-dance group. Elderly individuals who regularly practiced Tibetan dance had improved blood vessel functionality and cerebral hemodynamic at high altitudes.
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机译:评估青藏高原地区老年人血管相关因素和脑血流动力学的效果(平均高度≥2,300米)。三十名老年人,练习传统的西藏国庄舞或没有注册。通过ELISA测定法测量血清PGC-1α,HCY,FSTL-1,VEGF和HIF-1α。使用CUS和TCD评估颈动脉狭窄和斑块,IMT,颅外内部颈动脉狭窄和脑动脉粥样硬化。舞蹈组中体重,BMI,心率,收缩压,血清BGS,TC,LDL,HIF-1α,VEGF和HCY显着低于No-Dance Group。舞蹈组的FSTL-1水平,SO 2等2 /心率比显着高于No-Dance Group。颅内内部颈动脉狭窄的发病率,舞蹈群中的颈动脉狭窄和斑块明显低于无舞蹈团体。 IMT是No-Dance Group PGC-1α和Hcy之间的显着正相关。经常练习西藏舞蹈的老年人在高海拔地区改善了血管功能和脑血力学。
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