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首页> 外文期刊>PLoS One >Intraoperative cerebral oximetry in open heart surgeries reduced postoperative complications: A retrospective study
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Intraoperative cerebral oximetry in open heart surgeries reduced postoperative complications: A retrospective study

机译:开放性心脏手术中的术中脑血氧滴定术后术后并发症:回顾性研究

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摘要

Cardiothoracic surgeries are life-saving procedures but often it results in various complications. Intraoperative cerebral oximetry monitoring used to detect regional cerebral oxygen saturation (rScO2) is a non-invasive method that provides prognostic importance in cardiac surgery. The main aim of the present study was to evaluate the association of intraoperative cerebral oxygen monitoring during cardiac surgery on postoperative complications. This was a case-controlled retrospective study conducted on adult patients, who underwent open-heart surgery in National Heart Institute, Malaysia. The case group comprised patients on protocolized cerebral oximetry monitoring. They were treated using a standardized algorithm to maintain rScO2 not lower than 20% of baseline rScO2. The control group comprised patients with matched demographic background, preoperative risk factors, and type of surgical procedures. Propensity score stratification was utilized to contend with selection bias. Retrospective analysis was performed on 240 patients (case group) while comparing it to 407 patients (control group). The non-availability of cerebral oximetry monitoring during surgery was the prominent predictor for all outcome of complications; stroke (OR: 7.66), renal failure needing dialysis (OR: 5.12) and mortality (OR: 20.51). Postoperative complications revealed that there were significant differences for risk of mortality (p0.001, OR = 20.51), renal failure that required dialysis (p0.001, OR = 5.12) and stroke (p 0.05, OR = 7.66). Protocolized cerebral oximetry monitoring during cardiothoracic surgeries was found to be associated with lower incidence of stroke, renal failure requiring dialysis and mortality rate.
机译:心脏病的手术是挽救生命的程序,但它通常会导致各种并发症。用于检测区域脑氧饱和度(RSCO2)的术中脑血氧性监测是一种非侵入性方法,可提供心脏手术的预后重要性。本研究的主要目的是评估心脏手术期间术后并发症期间的术中脑氧监测的关联。这是对成年患者进行的案例控制的回顾性研究,在马来西亚国家心脏研究所接受露天手术。案例组组成患者于协议的脑血氧测量监测。它们使用标准化算法进行处理,以维持RSCO2不低于基线RSCO2的20%。该对照组包括患有匹配的人口背景,术前风险因素和外科手术类型的患者。倾向得分分层利用选择偏差。对240名患者进行回顾性分析(案例组),同时将其与407名患者(对照组)进行比较。在手术过程中脑血氧性监测的非可用性是所有并发症的所有结果的突出预测因子;中风(或:7.66),需要透析(或:5.12)和死亡率(或:20.51)。术后并发症表明,死亡率风险有显着差异(P <0.001,或= 20.51),所需透析所需的肾功能衰竭(P <0.001,或= 5.12)和中风(P <0.05,或= 7.66)。发现心脏病植物手术过程中的协议脑血氧测定监测与需要透析和死亡率的肾小序发病率降低,肾功能衰竭。

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