Incidence and quantification of corneal haze by Pentacam Scheimpflug densitometry following photorefractive keratectomy for myopia in virgin and post corneal transplant eyes with dark irides

摘要

Purpose: To assess the incidence and quantification of corneal haze after myopic photorefractive keratectomy in virgin and post corneal transplant eyes with dark irides.Methods: In this retrospective study at the tertiary eye hospital, the corneal haze was evaluated by slit-lamp and quantified by Pentacam Scheimpflug densitometry after myopic photorefractive keratectomy with mitomycin C in virgin eyes (group I) and post corneal transplant eyes (group II) with dark irides over 12 months.Results: Group I compromised 126eyes from 77patients (35males and 42females) aged 31.31 years (24.11–36.18 years), and group II compromised 44eyes from 33patients (18males and 15females) aged of 32.25 years (26.15–36.66 years). The incidence of corneal haze was 9.5% (95%CI: 5.0%–16%) and 6.8% (95%CI: 1.4–18.7%) in group I and II respectively (P = 0.587). The corneal densitometry was 22.69 ± 8.28GSU preoperatively and 17.98 ± 3.13GSU at 12 months postoperatively (P = 0.010) in group I. The corneal densitometry was 21.86 ± 6.22GSU preoperatively and 21.23 ± 4.29GSU at 12 months postoperatively (P = 0.815) in group II. High corneal maximal densitometry was associated with the thin central corneal thickness (P = 0.027), the presence of haze (P = 0.028), post-keratoplasty (P = 0.004), steep keratometry (P = 0.035).Conclusion: The incidence of corneal haze was comparable in virgin and post corneal transplant eyes. The Pentacam Scheimflug densitometry can be helpful in the diagnosis of corneal haze; however, the cutoff values need to be studied further in larger studies.