Exploration of the pathogenic factors of neonatal jaundice and the clinical effect of blue phototherapy

摘要

Objective: To study the pathogenic factors of neonatal jaundice and the clinical effect of blue light phototherapy. Methods: We selected 240 children with neonatal jaundice admitted to our hospital from January 2018 to January 2019 as the research subjects, and divided them into a control group and experimental group by a random grouping method, with 120 cases in each group. The control group received conventional treatment, and the experimental group received blue phototherapy. We observed the therapeutic effect on the two groups and analyzed the onset factors, compared the transcutaneous bilirubin value, serum bilirubin level, the time for the jaundice to subside after treatment, lactate dehydrogenase (LDH), creatine kinase (CK) in the myocardial enzyme spectrum, and alanine aminotransferase (ALT) and aspartate aminotransferase (AST) to show liver function. Results: Rate of effective treatment in the experimental group was higher than that in the control group. The transcutaneous bilirubin values and serum bilirubin levels of the two groups of children with jaundice were reduced after treatment (P0.001), and the decrease in the experimental group after treatment was more notable (P0.001). Jaundice subsided after treatment in the experimental group faster than in the control group (P0.001). Children with jaundice in the experimental group had lower indexes of LDH, CK, ALT and AST compared with those of the control group (P0.05). Conclusion: Phototherapy is a preferable method for neonatal jaundice and worthy of clinical application.