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Comprehensive nursing care on the psychological states, quality of life, and serum indexes of NSCLC patients with TCM combined with chemotherapy

机译:综合护理对心理状态,生活质量和NSCLC患者的生命质量和中医结合化疗的血清指数

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Objective: To study the effect of comprehensive nursing care on the psychological status, quality of life, and serum indicators of non-small cell lung cancer (NSCLC) patients undergoing traditional Chinese medicine (TCM) and chemotherapy. Methods: Ninety-two patients with NSCLC admitted to this hospital between January 2018 and June 2020 were recruited for this study. All the patients underwent combined Chinese medicine chemotherapy. The control group underwent conventional nursing care, and the observation group underwent comprehensive nursing. The clinical efficacy, lung function, serum indexes, quality of life, and psychological states of the two groups, their adverse reactions during the treatment period, and the patients’ satisfaction with the nursing work were compared. Results: The overall efficacy of the observation group was better in comparison with the control group. After the treatment, the PEF, FVC, and FEV1 levels in the observation group were higher than they were in the control group. After the treatment, the physical functioning, role functioning, emotional functioning, social functioning, and overall health scores in the observation group were higher than they were in the control group. The serum IL-6, TNF-α, and MMP-9 levels in the observation group were lower than they were in the control group. Regarding the incidence of nausea, vomiting, and diarrhea, the observation group had a lower incidence. In terms of of the total satisfaction rate, the observation group was better than the control group (97.83% vs 82.61%), and the differences were all statistically significant (P0.05). Conclusion: Comprehensive nursing can help improve the clinical efficacy of TCM combined with chemotherapy, reduce the serum indicator expression levels, improve the patients’ mental states and quality of life, improve patient satisfaction, and reduce the incidence of adverse reactions.
机译:目的:探讨综合护理对经历中医(中医)和化疗的非小细胞肺癌(NSCLC)患者的心理状态,生活质量和血清指标的影响。方法:2018年1月至6月20日至6月20日在这项研究中录取了本医院的92例NSCLC患者。所有患者都接受了中药化疗。对照组接受过常规护理,观察组接受综合护理。临床疗效,肺功能,血清指标,生活质量,以及两组的心理状态,治疗期间的不良反应,以及患者对护理工作的满意度。结果:与对照组相比,观察组的整体疗效更好。治疗后,观察组的PEF,FVC和FEV1水平高于对照组。治疗后,观察组中的物理功能,作用,情绪功能,社会功能和整体健康评分高于对照组。观察组中的血清IL-6,TNF-α和MMP-9水平低于对照组。关于恶心,呕吐和腹泻的发病率,观察组的发病率较低。就总满意率的总满意度而言,观察组优于对照组(97.83%vs 82.61%),差异均有统计学意义(P <0.05)。结论:综合护理有助于提高中医结合化疗的临床疗效,降低血清指针表达水平,改善患者的精神状态和生活质量,提高患者满意度,降低不良反应的发病率。

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