SYNTHESIS, ANTIMICROBIAL ACTIVITY AND DOCKING STUDIES OF 1-METHYL-3-(QUINOXALIN-2-YL) PYRROLIDIN-2-ONE

K.Srivani; E.Laxminarayana; M.Thirumala Chary

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SYNTHESIS, ANTIMICROBIAL ACTIVITY AND DOCKING STUDIES OF 1-METHYL-3-(QUINOXALIN-2-YL) PYRROLIDIN-2-ONE

机译：1-甲基-3-（喹喔啉-2-基）吡咯烷-2-甲基-3-（喹喔啉-2-基）的合成，抗微生物活性和对接研究

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摘要

The preparation of 1-methyl-3-(quinoxalin-2-yl)pyrrolidin-2-onewas described in a simple manner followed by green procedures, title compound was thoroughly characterized by IR, 1HNMR and mass spectra data. The resulted compounds 5, 6 and 7 screened for biological activity and docking studies results are presented.

机译：以简单的方式制备1-甲基-3-（喹喔啉-2-基）吡咯烷蛋白-2-蒽族，其次用绿色程序，通过IR，1HNMR和质谱数据彻底表征标题化合物。提出了用于生物活性和对接研究结果的所得化合物5,6和7。

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《Rasayan Journal of Chemistry》 |2021年第1期|共6页
作者
K.Srivani; E.Laxminarayana; M.Thirumala Chary;
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正文语种
中图分类化学;
关键词
Phosphorous oxychloridediethylmalonateLithium chloride2-bromo-11-dimethoxyethane;

机译：磷氧基氯酰氯丙酮酸锂2-溴-11-二甲氧基甲烷;

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1. Synthesis, Molecular Docking and evaluation of Antiangiogenic activity and Cellular metastasis potential of some Triazine and Pyrrolidin-2-one derivatives [J] . Ankit Kumar, Umesh Kumar Singh, Pratibha Gupta, Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry . 2016,第10期

机译：三嗪和吡咯烷基-2-酮衍生物的合成，分子对接及其抗血管生成活性和细胞转移潜力的评估
2. Synthesis, Antimicrobial Activity, Structure-Activity Relationship, and Molecular Docking Studies of Indole Diketopiperazine Alkaloids [J] . Bin Jia, Yang-min Ma, Bin Liu, Frontiers in Chemistry . 2019,第3期

机译：吲哚二酮哌嗪生物碱的合成，抗菌活性，结构活性关系和分子对接研究
3. Design, synthesis, biological evaluation, homology modeling and docking studies of (E)-3-(benzo[d][1,3]dioxol-5-ylmethylene) pyrrolidin-2-one derivatives as potent anticonvulsant agents [J] . Wang Tiantian, Dong Shiyang, Chen Xiaodong, Bioorganic and Medicinal Chemistry Letters . 2018,第8期

机译：（e）-3-（苯并[1,3]二氧戊醇-5-基甲基）吡咯烷-2-一种衍生物（E）-3-（苯并[D] [1,3]二氧戊醇-5-基甲基）吡咯烷蛋白-2-一种衍生物作为有效的抗惊厥药剂的设计，合成，生物学评价，同源造型和对接研究
4. Artificial Neural Network and Docking Study in Design and Synthesis of Xanthenes as Antimicrobial Agents [C] . Elma Veljovic, Selma Spirtovic-Halilovic, Samija Muratovic International Conference on Medical and Biological Engineering . 2017

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SYNTHESIS, ANTIMICROBIAL ACTIVITY AND DOCKING STUDIES OF 1-METHYL-3-(QUINOXALIN-2-YL) PYRROLIDIN-2-ONE

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