Effect of House Dust Mite Immunotherapy in Indonesian Children with Chronic Sinusitis

摘要

The aimed was associated to effect of HDM immunotherapy in children with chronic sinusitis due to HDM allergies. Participants were divided into 2 groups, consisting of treatment group (immunotherapy) with 23 patients, and control group with 22 patients. Treatment groups received HDM immunotherapy for 14 weeks. The statistical analysis used McNemar and Chi-Square test with 95% confidence interval (CI) and p <0.05. There was a significant difference in the improvement of Waters’ view in the treatment and control groups (p <0.001). There were significant differences in the absence of itchy nose symptom (p = 0.003), colored secretion (p = 0.024), itchy eyes (p = 0.019), wheezing (p = 0.024), shortness of breath (p = 0.039), sneezing (p <0.001), postnasal drip (p <0.001), stuffy nose (p <0.001), snoring (p <0.001), cough (p <0.001), phlegm (p <0.001), and rhinorrhea (p <0.001). There is an improvement in pediatric chronic sinusitis before and after HDM immunotherapy.