Binding Capability and Non–biofouling Efficacy of Poly[2‐(methacryloyloxy)ethyl‐4‐pentynoate‐co‐oligo(ethylene Glycol) Methacrylate] Films on Gold Surfaces

摘要

We demonstrated the binding capability and non‐biofouling efficacy of biotinylated, poly(MAEP‐co‐OEGMA) films using streptavidin and fibrinogen. The copolymeric films were synthesized on gold substrates without activation or passivation via the surface initiated‐controlled radical polymerization of MAEP and OEGMA in five different molar ratios, followed by biotinylation using “click” chemistry. The copolymeric film synthesized with MAEP at a mole fraction of 0.2 exhibited the best performance of surface plasmon resonance.