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The development of a wireless LCP-based intracranial pressure sensor for traumatic brain injury patients

机译:用于创伤性脑损伤患者的无线LCP基颅内压传感器的发展

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Raised intracranial pressure (ICP) in traumatic brain injury (TBI) patients can lead to death. ICP measurement is required to monitor the condition of a patient and to inform TBI treatment. This work presents a new wireless liquid crystal polymer (LCP) based ICP sensor. The sensor is designed with the purpose of measuring ICP and wirelessly transmitting the signal to an external monitoring unit. The sensor is minimally invasive and biocompatible due to the mechanical design and the use of LCP. A prototype sensor and associated wireless module are fabricated and tested to demonstrate the functionality and performance of the wireless LCP-based ICP sensor. Experimental results show that the wireless LCP-based ICP sensor can operate in the pressure range of 0 - 60.12 mmHg. Based on repeated measurements, the sensitivity of the sensor is found to be 25.62 μVmmHg-1, with a standard deviation of ± 1.16 μVmmHg-1. This work represents a significant step towards achieving a wireless, implantable, minimally invasive ICP monitoring strategy for TBI patients.
机译:在创伤性脑损伤(TBI)患者中提高颅内压(ICP)可以导致死亡。需要ICP测量来监测患者的状况并告知TBI治疗。这项工作介绍了一种基于新的无线液晶聚合物(LCP)的ICP传感器。该传感器的设计目的是测量ICP并将信号无线传输到外部监控单元。由于机械设计和LCP的使用,传感器由于机械设计和使用而是微创和生物相容的。制造和测试了原型传感器和相关的无线模块,以演示基于无线LCP的ICP传感器的功能和性能。实验结果表明,基于无线LCP的ICP传感器可以在0-60.12mmHg的压力范围内运行。基于重复测量,发现传感器的灵敏度为25.62μVMMHG-1,标准偏差为±1.16μVMMHG-1。这项工作代表了实现TBI患者的无线,植入,微创ICP监测策略的重要一步。

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