Role of Plasma Exchange in Steroid Resistant Neuromyelitis Optica with Loss of Vision

摘要

Neuromyelitis Optica (NMO) is a demyelinating inflammatory disorder of the spinal cord and optic nerve. As per American SocietyFor Apheresis (ASFA) guidelines, Therapeutic Plasma Exchange (TPE) is considered as a second-line treatment in patients withweak or no response to steroid therapy. A patient of NMO presented to the tertiary care institute with the sudden loss of vision inthe right eye. The patient was resistant to steroid treatment and improved significantly with TPE. Hence, TPE may be an effectivetreatment modality in steroid-resistant NMO with vision loss.