Serum Uric Acid Levels and Serum Lipid Levels in Patients with Ischemic Cerebrovascular Accident

摘要

Background: Stroke is a growing disease and it is the second common causeof death in the world after coronary heart disease especially in the elderly. Inpatients with acute stroke hyperuricemia was significantly higher than normalpopulation with associated dyslipidemia. Hyperuricemia has been associated withdecreased amount of HDL cholesterol and increased amounts of triglyceridesand LDL cholesterol.Aim: Serum uric acid levels and serum lipid levels in patients with ischemiccerebrovascular accident.Material and Methods: This was a cross-sectional study carried out betweenJanuary 2015 - June 2016, which included 60 cases of acute ischemic stroke.Serum uric acid levels and serum lipid levels was done in all the patients andwas statistically analyzed.Result: A total of 60 patients with ischemic stroke were included in the study. Outof which 43 (71.7%) were males and 17 (28.3%) were females. The mean age ofthe patients was 63.2 ±14.8. Mean serum uric acid levels in the patients studiedwas 5.5 ± 1.7, and 18 patients (30%) were hyperuricemic. Serum uric acid levelswere significantly higher in females (6.2 ± 1.9) compared to the males (5.2 ±1.6).It was predominant in the age group between 56-70 years. Dyslipidemia wasseen in 49 (81.7%) patients (Males were 36 and females were 13).. More thanone lipid parameter was seen to be deranged in 10 male patients and 4 femalepatients. Of them 87.75% of patients had low HDL levels, 36.73%, 10.20% and8.16% patient had high cholesterol, triglycerides and LDL levels respectively. Thestudy also showed that 15 patients had both hyperuricemia and dyslipidemia.Conclusion: Hyperuricemia and its accompanying dyslipidemia can be consideredas the risk factor for acute ischemic stroke.