Case Report of Childhood-Onset Psychosis in a Patient with a Known WNT10A Mutation

摘要

Objective To report on a patient with childhood-onset psychosis at age 12 with a known WNT10A mutation. Methods Case report. Results The patient is a 12-year-old male who presented with an acute onset of psychosis in the context of a known WNT10A mutation. Conclusion WNT genes have only been previously linked to schizophrenia on a theoretical basis. To our knowledge, this is the first case report of an association between a childhood-onset psychosis and a WNT10A mutation. We conclude that there is a possibility that WNT10A may be one of the many genes contributing to the development of childhood-onset schizophrenia.