Nutraceuticals 2020 Preparation and Evaluation of a Novel instant Drug Delivery System (iDDS) for Nutraceutical and Pharmaceutical Active Ingredients

摘要

The present work is related to the development and evaluation of a novel instant drug delivery system for the Active Ingredients that are used commonly in the nutraceutical and pharmaceutical preparations. This technology can be utilized for the availability of these active ingredients in-vivo much faster than the traditional particulate drug delivery systems. The preparation of these formulations involves the development of an innovative process for the conversion of active ingredient in a molecular form/nano dispersion in a suitable matrix which can be either presented in a final dosage form of tablets, capsules, dry syrups, suspensions etc. This novel active drug matrix has been named as a??iAgglomeratesa??. The present delivery system ie iAgglomerates matrix can be used for diversified range of active ingredients which can help in significant clinical outcome of a nutraceutical or pharmaceutical product. Traditional nutraceuticals and cosmeceuticals hold pragmatic nature with respect to their definitions, claims, purposes and marketing strategies. Their definitions are not well established worldwide. They also have different regulatory definitions and registration regulatory processes in different parts of the world. Global prevalence of nutraceuticals and cosmeceuticals is noticeably high with large market share with minimal regulation compared to traditional drugs. The global market is flooded with nutraceuticals and cosmeceuticals claiming to be of natural origin and sold with a therapeutic claim by major online retail stores such as Amazon and eBay. Apart from the traditional formulations, many manufacturers and researchers use novel formulation technologies in nutraceutical and cosmeceutical formulations for different reasons and objectives. Manufacturers tend to differentiate their products with novel formulations to increase market appeal and sales. On the other hand, researchers use novel strategies to enhance nutraceuticals and cosmeceuticals activity and safety.