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3D‐printed headrest for frameless Gamma Knife radiosurgery: Design and validation

机译:无框伽马刀放射外科服务的3D印刷头枕:设计与验证

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Purpose Frameless Gamma Knife stereotactic radiosurgery (SRS) uses a moldable headrest with a thermoplastic mask for patient immobilization. An efficacious headrest is time consuming and difficult to fabricate due to the expertise required to mold the headrest within machine geometrical limitations. The purpose of this study was to design and validate a three‐dimensional (3D)‐printed headrest for frameless Gamma Knife SRS that can overcome these difficulties. Materials and methods A headrest 3D model designed to fit within the frameless adapter was 3D printed. Dosimetric properties of the 3D‐printed headrest and a standard‐of‐care moldable headrest were compared by delivering a Gamma Knife treatment to an anthropomorphic head phantom fitted with an ionization chamber and radiochromic film. Ionization measurements were compared to assess headrest attenuation and a gamma index was calculated to compare the film dose distributions. A volunteer study was conducted to assess the immobilization efficacy of the 3D‐printed headrest compared to the moldable headrest. Five volunteers had their head motion tracked by a surface tracking system while immobilized in each headrest for 20?min. The recorded motion data were used to calculate the average volunteer movement and a paired t‐test was performed. Results The ionization chamber readings were within 0.55% for the 3D‐printed and moldable headrests, and the calculated gamma index showed 98.6% of points within dose difference of 2% and 2?mm distance to agreement for the film measurement. These results demonstrate that the headrests were dosimetrically equivalent within the experimental uncertainties. Average motion (±standard deviation) of the volunteers while immobilized was 1.41?±?0.43?mm and 1.36?±?0.51?mm for the 3D‐printed and moldable headrests, respectively. The average observed volunteer motion between headrests was not statistically different, based on a P ‐value of 0.466. Conclusions We designed and validated a 3D‐printed headrest for immobilizing patients undergoing frameless Gamma Knife SRS.
机译:无可用的无可可用的伽马刀立体定向放射炮(SRS)使用可模塑头枕,具有热塑性面膜,用于患者固定。由于在机床几何限制内铸造头枕所需的专业知识,有效的头枕是耗时且难以制造的。本研究的目的是设计和验证三维(3D) - 用于克服这些困难的无框伽马刀SRS打印头枕。材料和方法设计适合无框适配器的头枕3D模型是印刷的3D。通过将伽马刀处理递送到装有电离室和放射圆形膜的拟蒽型磁头模体,比较3D印刷头枕的剂量性能和护理标准可模塑头枕。比较电离测量以评估头枕衰减,并计算伽马指数以比较薄膜剂量分布。进行了志愿者研究以评估与可模塑的头枕相比的3D印刷头部的固定效果。五个志愿者通过表面跟踪系统进行了头部动作,同时在每个头枕中固定在每个头枕20?min。记录的运动数据用于计算平均志愿者运动,并进行配对的T检验。结果3D印刷和可模重型的电离室读数在0.55%以内,计算出的伽马指数显示出98.6%的点,剂量差为2%和2毫米距离薄膜测量的距离。这些结果表明,在实验的不确定性中,头枕在微量异细胞上等同物。志愿者的平均运动(±标准偏差)分别为1.41?±0.43Ω·mm和1.36?±0.51Ω·±0.51Ω·mm,分别用于3D印刷和可模的头枕。基于0.466的P-value,头枕之间的平均观察到的志愿者动作并没有统计学不同。结论我们设计并验证了一种用于固定接受无框伽玛刀SRS的患者的3D印刷头枕。

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