Data on the application of the focused beam reflectance measurement (FBRM): A process parameters dataset for the ethyl cellulose (EC) microparticles preparation by the solvent evaporation method

摘要

The data article refers to the paper “Effect of solvent type on preparation of ethyl cellulose microparticles by solvent evaporation method with double emulsion system using focused beam reflectance measurement” . Data presented here include the effect of solvent type, method of emulsification (an oil-in-water (O/W) or a water-in-oil-in-water (W/O/W)), external aqueous phase volume, stirring speed and ethyl cellulose concentration on the preparation of ethyl cellulose microparticles. Data also refer to the effect of above mentioned factors on the solidification rate, hardening time, particle size, particle size mean, chord length distribution (CLD) and chord count of microparticles. Additionally, data exhibit process parameters when emulsion droplets transformed into solid microparticles during fabrication. The transformation of the emulsion droplets into solid microparticles occured within the first 10, 10.5, 12 and 60 minutes (O/W), and the first 12, 11.5, 10 and 90 minutes (W/O/W) when dichloromethane/methanol (1:1), dichloromethane, ethyl acetate and chloroform were used respectively. Either in O/W and W/O/W emulsion system, Chloroform gave smallest square weighted mean chord length. In contrast, its chord counts was not to be the highest.