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Data describing the association between rs266729 polymorphism inadiponectin promoter gene and Type 2 Diabetes Mellitus

机译:描述RS266729多态性iniponectin启动子基因和2型糖尿病之间的关联的数据

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This article investigates whether there is an association between the rs266729 polymorphism in adiponectin promoter gene with metabolic parameters and disease status in 300 type 2 diabetes patients and 300 healthy adults from Jahrom city, Iran. The variants (G/C) were tested by polymerase chain reaction-restriction fragment length polymorphism method (RFLP) and metabolic parameters (glucose, cholesterol, HDL and LDL cholesterol) were measured using biochemical methods. However, no differences were detected between the haplotypes investigated, and the data obtained from our lab shown association of the ADIPOQ promoter polymorphism neither with biochemical parameters, nor with disease status.
机译:本文调查脂联素启动子基因的RS266729多态性与300型糖尿病患者的代谢参数和疾病状态,来自伊朗的Jahrom市300型糖尿病患者和300名健康成人。通过聚合酶链反应限制片段长度多态性方法(RFLP)和代谢参数(葡萄糖,胆固醇,HDL和LDL胆固醇)测试变体(G / C),使用生化方法测量代谢参数(葡萄糖,胆固醇,HDL和LDL胆固醇)。然而,在研究单倍型之间没有检测到差异,并且从我们的实验室所显示的数据显示adipoq启动子多态性的关联既不是生物化学参数,也没有疾病状态。

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