Advances in biological immunotherapy for gastric cancer: a mini-review

摘要

Highlights Gastric cancer is a malignant tumor that originates in the gastric mucosa. Due to various factors, the treatment effect of gastric cancer patients is not ideal and appears younger. Gastric cancer immunotherapy refers to the use of biotechnology to mobilize immune functions so that people have natural anti-cancer capabilities. This article summarizes the research progress of biological immunotherapy for gastric cancer. Gastric cancer immunotherapy refers to the use of biological technology to mobilize the immune function so that the body has a natural anti-cancer ability. It can be induced in vitro by collecting immune cells and cancer cells from patients with gastric cancer to form specific immune cell groups. Besides, a large number of these immune cell groups are cultured, separated, and then reinfused into patients, to achieve high efficiency, eliminate tumors and mobilize immune mechanisms in patients. In theory, this method can cure tumors because the principle of immunotherapy is to stimulate the body's autoimmune response. However, for some special populations, there may be more severe side effects. At present, the prediction, prevention, and treatment of this severe side effect are not complete. The immunotherapy of gastric cancer has not yet reached the full promotion, but it is a good treatment direction. It can be used clinically with chemotherapy and radiotherapy, surgery and traditional Chinese medicine cooperate, thereby achieving significant curative effects, and even curing gastric cancer.