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Investigation and analysis of a fluidized bed dryer by process tomography sensor

机译:工艺断层扫描传感器的流化床烘干机调查分析

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In the pharmaceutical industry, fluidized beds are typically used for pellets drying, coating and granulation. The gas–solids flow characteristic in the process plays an important role to control the heat and mass transfer as well as the end-point product quality. Therefore, it is necessary to investigate the flow characteristics based on advanced measurement technologies. In this research, electrical capacitance tomography (ECT) sensor with eight electrodes was used to investigate the pharmaceutical fluidized bed drying process with different operation conditions. Key process parameters including solids concentration, particle moisture and capacitance signals in the process are given and analysed based on the ECT sensor. In addition, the fluidized bed process with Wurster tube is also investigated based on this ECT sensor. The effect of Wurster tube on the hydrodynamic behaviour and the dominant frequency spectrum distribution in the chamber were analysed based on fast Fourier transform. Test results reveal that process moisture change can be addressed from the raw capacitance of adjacent electrode pair combined with calibration model. Experimental result also indicates that ECT technology can provide useful information for process monitor in a fluidized bed dryer.
机译:在制药行业中,流化床通常用于颗粒干燥,涂布和造粒。该过程中的气体固体流动特性起到控制热量和质量传递以及终点产品质量的重要作用。因此,有必要研究基于高级测量技术的流动特性。在该研究中,使用具有八个电极的电容断层扫描(ECT)传感器来研究具有不同操作条件的药物流化床干燥过程。基于ECT传感器给出并分析包括固体浓度,颗粒湿度和电容信号的钥匙工艺参数。此外,还基于该ECT传感器研究了具有纬管管的流化床工艺。基于快速傅里叶变换,分析了纬管对腔室流体动力学行为的影响及腔室中的主要频谱分布。测试结果表明,可以从相邻电极对与校准模型的原始电容寻址过程湿度变化。实验结果还表明ECT技术可以为流化床干燥器中的过程监测器提供有用的信息。

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