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首页> 外文期刊>Saudi Pharmaceutical Journal >Natural products against cancer: Review on phytochemicals from marine sources in preventing cancer
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Natural products against cancer: Review on phytochemicals from marine sources in preventing cancer

机译:对抗癌症的天然产品:对癌症预防癌症的植物来源评论

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摘要

Marine natural products have as of now been acknowledged as the most important source of bioactive substances and drug leads. Marine flora and fauna, such as algae, bacteria, sponges, fungi, seaweeds, corals, diatoms, ascidian etc. are important resources from oceans, accounting for more than 90% of the total oceanic biomass. They are taxonomically different with huge productive and are pharmacologically active novel chemical signatures and bid a tremendous opportunity for discovery of new anti-cancer molecules. The water bodies a rich source of potent molecules which improve existence suitability and serve as chemical shield against microbes and little or huge creatures. These molecules have exhibited a range of biological properties antioxidant, antibacterial, antitumour etc. In spite of huge resources enriched with exciting chemicals, the marine floras and faunas are largely unexplored for their anticancer properties. In recent past, numerous marine anticancer compounds have been isolated, characterized, identified and are under trials for human use. In this write up we have tried to compile about marine-derived compounds anticancer biological activities of diverse flora and fauna and their underlying mechanisms and the generous raise in these compounds examined for malignant growth treatment in the course of the most recent quite a long while.
机译:海洋天然产品现在已被视为生物活性物质和药物引线最重要的来源。海洋植物群和动物群,如藻类,细菌,海绵,真菌,海藻,珊瑚,硅藻,阿丙基尼斯等是来自海洋的重要资源,占海洋生物量的90%以上。它们与巨大的生产力不同,具有巨大的生产性,并具有药理学活跃的新型化学特性,并出价了发现新的抗癌分子的巨大机会。水体是丰富的有效分子来源,可改善存在适合性,并用作对微生物和少数或巨大生物的化学屏蔽。这些分子表现出一系列生物学性质抗氧化剂,抗菌,抗肿瘤等,尽管富有令人兴奋的化学品富裕的资源,海洋植物群和动物群主要对其抗癌性质而言。最近,已经分离了许多海洋抗癌化合物,其特征,鉴定,并受到人类使用的试验。在这篇写作中,我们试图编制了各种植物和动物群的海洋衍生的化合物抗癌生物学活动及其潜在的机制,以及在最近一段时间内的恶性生长治疗中检查的这些化合物中的慷慨提升。

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