Candida balanitis. Clinical and mycological study about the efficacy of a single-day oral treatment with itraconazole (400 mg)

摘要

Objective: To assess the efficacy of a single dose of itraconazole (400mg/day), divided into two doses in the treatmentof Candida balanitis. Material and Methods: We carried out a prospective, non-compared study in patients withclinically verified Candida balanitis and through direct examinations, stains and cultures. Each of the patients wasgiven a treatment scheme of itraconazole 400mg/day, divided into two doses. Revisions were carried out at baseline andsubsequently on days 3, 7, and 15. Results: We included 26 cases, with an average age of 43.5 years. A predominanceof Candida albicans was obtained in 69.2% and the remaining were Candida non-albicans species. At the end ofthe treatment and follow-up for 7 days, clinical and mycological cure was obtained in 22/26 patients (84.6%). Sideeffects were presented in two patients (7.7%), one with moderate dyspepsia and the other with moderate headache.Conclusion: The treatment of Candida balanitis with a single dose of 400mg of oral itraconazole is effective, welltolerated and represents a new therapeutic alternative of short duration.