Rosa mosqueta como potencial agente cicatrizante

摘要

Introduction: The oil extracted of Rose hip’ seeds (Rosa aff rubiginosa or Rosa canina L.) is rich in fatty acids and transretinoic acid whose properties have attracted the interest this input in the healing process. Objective: To conduct a survey of studies on topical application of rosehip oil for wound healing. Methods: The search was conducted on electronic databases between july and September 2015 using the following descriptors: “Rosa Mosqueta”, “wound”, “Rosa aff rubiginosa”, “healing” ou “Rosa canina”, which included original and review articles. We found 7 publications: one literature review, three non-clinical experimental studies, one clinical study of non-experimental design, one study of quasi-experimental design and the other with experimental design, but low methodological quality. Conclusions: The studies show that in healing by first intention, the oil must be used 48h after the procedure. The refined oil is more stable than the crude oil and maintain therapeutic effects even at lower concentrations. However, clinical studies contain methodological bias to reduce the level of evidence and are not sufficient for appropriate recommendation. The non-clinical studies show that rosehip oil may have immunomodulatory activity in wound bed and promotes collagen deposition and tissue organization.