首页> 外文期刊>Radiology and Oncology >Genetic markers in oligodendroglial tumours
【24h】

Genetic markers in oligodendroglial tumours

机译:脱霉素肿瘤中的遗传标记

获取原文
       

摘要

Background. Oliogodendrogliomas are brain tumours composed of the cells resembling oligodendrocytes. They represent the third most common glial tumour, comprising 2.5% of all primary brain tumours and 5-20% of all gliomas.Conclusions. Oligodendroglial tumours with 1p and 19q loss demonstrate a better overall prognosis due to more indolent clinical behaviour and higher sensitivity to treatment. Additionally, 1p and 19q loss is a marker of clinical utility, helping to assess tumour sensitivity to chemotherapy and harbouring the potential for improving the diagnosis and survival of oligodendroglioma patients as well as future clinical practice.
机译:背景。 OlioGodendrogliomas是由类似于少突胶质细胞的细胞组成的脑肿瘤。它们代表了第三种最常见的胶质肿瘤,包含所有原发性脑肿瘤的2.5%,占所有Gliomas的5-20%。结论。具有1P和19Q损失的少曲面肿瘤表现出由于更惰性的临床行为和对治疗较高的敏感性而具有更好的整体预后。此外,1P和19Q损失是临床实用性的标志物,有助于评估肿瘤对化疗和患有改善少突患者诊断和存活的潜力以及未来的临床实践。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号