SAT-151 A DILEMMA OF CALCITRIOL IN PRE-DIALYTIC CHRONIC KIDNEY DISEASE: A 1-YEAR STUDY FOR COMBINATION THERAPY OF CALCITRIOL AND RENIN-ANGIOTENSIN ALDOSTERONE BLOCKER IN CHRONIC KIDNEY DISEASE

摘要

Introduction: Renin-angiotensin aldosterone system blockers (RASB) ismain stream of management of chronic kidney disease (CKD). Vitamin D(vitD) is known as a potent negative regulator of renin-angiotensinaldosterone system via vitamin D receptor. VitD deficiency often pre-sents, even in early CKD. However, there is no a definite guideline ofuse of vitD in CKD. In addition, the use of vitD should be given acareful attention due to development of hypercalcemia or vascularcalcification in CKD. Now, we report results of a 1-year study forcombination therapy of calcitriol and RASB in patients with pre-dia-lytic CKD and vitD deficiency.