The first two talks concerned the regulation of nuclear structure.Pan Chen (Levy lab, University of Wyoming) used Xenopus extractsand microfluidics to show that cytoplasmic volume contributes tothe regulation of nuclear size, finding that the amount of the histonechaperone nucleoplasmin limits nuclear growth by influencing chromatinorganization (Chen et al., 2019). Tina Tootle (University ofIowa) showed that actin localizes to the nucleolus during Drosophilaoogenesis and that prostaglandin signaling negatively regulatesnuclear actin localization to maintain proper nucleolar structure.
展开▼
机译：前两次谈判涉及核结构的监管。陈陈（征收实验室，怀俄明大学）使用异种萃取物和微流体表明，细胞质体积有助于调节核规模，发现通过影响的组核状核质核素限制核增长染色体组织（Chen等，2019）。 Tina Tootle（ofiowa大学）显示肌动蛋白在果蝇期间定位于核仁，并且前列腺素信号传导负调节核肌动蛋白定位以保持适当的核仁结构。
展开▼
