Factors Influencing Health-Related Quality of Life of Living-Donor Kidney Transplant Recipients: A Population-Based Study

摘要

Objectives: Our objective was to explore factors influencing health-related quality of life in living-donor kidney transplant recipients. Materials and Methods: A total of 140 kidney transplant recipients, enrolled between December 2014 and April 2015, were administered questionnaires on medical outcomes, 36-item Short Form Health Survey, medical coping modes, cognitive appraisal of health scale, and adverse effects of medications. Path analysis was employed to verify the hypothesized model. Results: Increased serum creatinine level and high economic burden had direct positive effects on negative appraisal (β = 0.18, P P P P P P Conclusions: In this study, economic burden, serum creatinine levels, and adverse effects of immuno-suppressive therapy were the key external factors, whereas patients’ cognitive appraisal and coping strategies were the main internal factors affecting patients’ health-related quality of life. Medical care providers attending to transplant recipients should be able to identify patients developing negative coping strategies in response to stressors and plan indi-vidualized counseling programs for these patients.