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Cancer Risk Assessment for Workers Exposed to Pollution Source, a Petrochemical Company, Iran

机译:患有污染源的工人癌症风险评估,石油化工公司,伊朗

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Background: Air pollution have led to severe problem of adverse health effect in the world. This study aimed to conduct the health risk assessment, cancer risk analysis, and non-cancer risk for exposure to volatile organic compounds (VOCs) and hydrogen sulfide (H2S) in petrochemical industry. Methods: In this cross-sectional research, 123 samples were collected in the ambient air in Iran during winter 2016. For sampling and analysis of VOCs and H2S, 3 methods (numbers 1500, 1501, and 6013) presented by the National Institute of Occupational Safety and Health (NIOSH) were used. For determination of risk assessment of chemical pollutants, semi-quantitative method presented by the Occupational Safety and Health Division, Singapore was used. Finally, for calculation of cancer risk analysis, Chronic Daily Intake (CDI) and calculation of non-cancer risk, Exposure Concentration (EC) were used. Results: Average concentration of benzene (2.12±0.95) in breathing zone of workers were higher than the Threshold Limit Values-Time Weighted Average (TLV-TWA) (P0.05). Among chemical substance, benzene had very high rank of risk in petrochemical industry. Rank of risk for H2S, toluene, and xylene present in the breathing zone of workers was low. The mean cancer risk for workers exposed to benzene was estimated 8.78×10-3, in other words, 8.7 cancer per 1000 i.e. higher than the acceptable standard of 10-6. In our study, non-cancer risk for BTX was higher than the acceptable standard of 1. Conclusion: In particular, overall cancer and toxic risk can be associated with long term exposure to benzene.
机译:背景:空气污染导致了世界上不良健康影响的严重问题。本研究旨在进行暴露于石化工业中挥发性有机化合物(VOC)和硫化氢(H2S)的健康风险评估,癌症风险分析和非癌症风险。方法:在这种横截面研究中,在2016年冬季,在伊朗的环境空气中收集了123个样品。用于对国家职业研究所提供的VOC和H2S的抽样和分析,3种方法(第1500,1501和6013号)使用安全和健康(Niosh)。用于测定化学污染物的风险评估,使用了新加坡职业安全和健康司的半定量方法。最后,为了计算癌症风险分析,使用慢性每日摄入(CDI)和非癌症风险的计算,使用曝光浓度(EC)。结果:工人呼吸区苯(2.12±0.95)的平均浓度高于阈值限值 - 时间加权平均值(TLV-TWA)(P <0.05)。化学物质中,苯在石油化工行业中具有很高的风险。在工人呼吸区中存在H2S,甲苯和二甲苯的风险等级低。估计暴露于苯的工人的平均癌症风险估计为8.78×10-3,换句话说,每1000即癌症8.7癌症。高于10-6的可接受标准。在我们的研究中,BTX的非癌症风险高于可接受的1.结论:特别是,整体癌症和有毒风险可能与长期暴露于苯。

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