HiVis: a portable, scalable tool for hierarchical visualization and analysis of biological networks

摘要

It is very important to analyze the network structure of interacting genes, proteins, RNAs, etc. in large-scale biological networks which represent complex biological systems. Many tools have been made for this purpose. However, they are either unable to display the hierarchically structured view of the networks or not easy to build in cross-platforms. Here, we present a navigation tool called HiVis for biological network visualization. HiVis provides a hierarchical view of the networks through a zoom-in or zoom-out function powered by k-means and fast approximate spectral clustering algorithms. It is a cross-platform, portable, fast desktop application to large-scale networks.