Survival Analysis of Cancer Patients Treated with Traditional Korean Medicine Recent 10 years

摘要

Purpose: We aimed to analyze survival rates and durationof cancer patients who treated with Traditional KoreanMedicine (TKM).Methods: We analyzed the medical records of 971 patientswhowere treated more than 1 month of out-patient or 20 daysof hospitalization at the Daejeon Oriental Hospital from Oct.2004 to Sep. 2014. The survival rates and median survival duration(MSD) were estimated by the Kaplan-Meier method andLog-rank test. Seven different kinds of cancers patients whowere suffered from liver, thyroid, colon & rectum, stomach,breast, pancreas, or lung cancer were analyzed by gender, age,and cancer stage-specific. We also estimated survival ratesand MSD of 203 terminally ill cancer patients.Results: The 5-year survival rates and MSD of 971 patientswas 38.6% (95%CI 34.8 – 42.3), 3.28-year (95%CI 2.87 - 3.65)respectively. The 5-year survival rates of liver, colon & rectum,stomach, breast, pancreas and lung cancer patientswere30.0% (95% CI 19.5 – 40.5), 25.0%(95% CI 16.0 – 34.0), 24.4%(95%CI 16.2 – 32.6), 79.3%(95% CI 70.4 – 88.1), 3.4% (95% CI 0.0 –9.3), 22.2%(95% CI 12.6 – 31.8), respectively. The MSD for liver,colon & rectum, stomach, breast, pancreas and lung cancerpatients was 2.27-year (95%CI 1.21 - 3.50), 3.11-years (95%CI2.67 - 3.58), 1.96-year (95%CI 1.71 - 2.52), 8.04-year (95%CI 7.01- 10.69), 1.01-year (95% CI 0.80 - 1.21), 2.07-years (95%CI 1.47 -2.53), respectively. Moreover, the MSD of terminally ill cancerpatientswas 0.39-years (about 20weeks, 95%CI 0.33 - 0.44) and0.5-year survival rates for them were 40.7% (95%CI 33.6 - 47.7),respectively.Conclusion: All cancer types were not obviously extendedthe survival duration by treatment with TKM, the survivalrate, especially for the liver, breast, pancreas and lung cancerpatients are relatively higher than other treatment.Well-designed and prospective clinical trials should be recommendedto provide more reliable evidence.