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首页> 外文期刊>Indian Journal of Ophthalmology >Intraocular IgG4 disease masquerading as nodular scleritis
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Intraocular IgG4 disease masquerading as nodular scleritis

机译:伪装成结节性硬化性的眼内IgG4疾病

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A37-year-old gentleman presented with complaints ofredness in lefteye of 4 months duration and blurring of vision of 1 month duration. He was referred with a diagnosis ofscleritisand was being treated with topicaland oralsteroids since 3 months but remained symptomatic. He did not haveany systemiccomorbidities. Bestcorrected visualacuitywas 6 / 6. Anterior segmentexamination revealed diffusescleritis with anterior uveitis. Posterior segmentexamination showed exudativeretinal detachment with choroidal detachment, with overlying vitreous hazein the inferotemporal quadrantcorresponding to thearea ofscleritis. Rheumatoid factor was negativeand antinuclearantibody by indirect immunofluorescence was negative. C-reactive proteinwas 6 mg/L,erythrocytesedimentation rate was 10 mm/h. As thescleritis was not responding to steroids he was started on oralmethotrexate 15 mg/week with folicacid. After 2 months ofimmunosuppressivetherapy, there was no improvementand the visionworsened to 3 / 60. Examination revealed aretroiridaltumor in thetemporal halfwith distorted pupil, shallow anteriorchamber,circumcornealcongestion, panuveitis with scleritis,and increased intraocular pressure[Figure 1]. Ultrasound biomicroscopy revealed a homogenous reflective,echoeicciliary bodymass, measuring 4.6 × 3.7 mm,extending from2 to 6 O' clock positionwith overlying episcleralthickening and nasally subluxated lens [Figure 2]. Positron emission tomography revealed no extraocular spread or metastasis.
机译:A37岁的绅士在4个月持续时间和1个月持续时间的持续时间内呈现出伤害4个月。他被诊断诊断,自3个月以来,在局部和oralterkoids被治疗,但仍然存在症状。他没有Haveany System.酿造的Visualacitywas 6 / 6.前分析探测揭示了前葡萄炎的扩散静脉炎。后部分析显示出与脉络膜脱离的横向性脱离,覆盖玻璃体雾蛋白,对应于颅内炎的那段常普朗特。随着间接免疫荧光是阴性的,类风湿因子是否定的抗胰腺剂。 C-反应蛋白瓦斯<6mg / L,红细胞等待率为10mm / h。由于体内炎未响应类固醇,他开始于oralmethot克己续15毫克/周与叶酸裂解。在2个月后,MunosUppressivEspiverAppace,Visionworsened含量没有改善和3/60.检查揭示了血珠半孢子,浅前探针,割礼,血管炎的血管炎的aretroiridaltumor,以及肝炎的血管炎,并增加了眼压的增加[图1]。超声波生物显微镜显示出同质反射,回声杆菌体,测量4.6×3.7毫米,从2至6℃的时钟位置延伸,覆盖外克隆和鼻子上限镜头[图2]。正电子发射断层扫描显示出不显示出非潜在的传播或转移。

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