Variability is observed at multiple-scales in the brain and ubiquitous in perception. However, the nature of perceptual variability is an open question. We focus on variability during perceptual rivalry, a form of neuronal competition. Rivalry provides a window into neural processing since activity in many brain areas is correlated to the alternating perception rather than a constant ambiguous stimulus. It exhibits robust properties at multiple scales including conscious awareness and neuron dynamics. The prevalent theory for spiking variability is called the balanced state; whereas, the source of perceptual variability is unknown. Here we show that a single biophysical circuit model, satisfying certain mutual inhibition architectures, can explain spiking and perceptual variability during rivalry. These models adhere to a broad set of strict experimental constraints at multiple scales. As we show, the models predict how spiking and perceptual variability changes with stimulus conditions. Benjamin P Cohen, Carson C Chow, and Shashaank Vattikuti show that dynamical mutual inhibition models can explain variability during neuronal competition at two scales: neuronal spiking activity and perceptual rivalry variability. These models make predictions for how spiking and perceptual variability will change with stimulus conditions.
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机译:在大脑中的多尺度和感知中无处不在地观察到变异性。然而,感知变异性的性质是一个开放的问题。我们专注于感知竞争期间的可变性,一种神经元竞争。竞争为神经处理提供了一个窗口,因为许多脑区域中的活动与交替感知而不是恒定的模糊刺激相关。它在多种尺度上表现出强大的属性,包括有意识的意识和神经元动力学。尖峰变异性的普遍理论称为平衡状态;虽然,感知变异性的来源是未知的。在这里,我们表明,一个满足某些相互抑制架构的单一生物物理电路模型可以解释竞争期间的尖峰和感知变化。这些型号坚持多尺度的广泛严格的实验约束。正如我们所展示的那样,模型预测尖刺和感知可变性如何随着刺激条件而变化。 Benjamin P Cohen,Carson C Chow和Shashaank Vattikuti表明,动态互抑制模型可以在两种尺度的神经元竞争中解释可变性:神经元尖峰活动和感知竞争变异性。这些模型对刺激条件改变了尖刺和感知变异的预测。
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