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Minimum 8-year follow-up of revision THA with severe femoral bone defects using extensively porous-coated stems and cortical strut allografts

机译:使用广泛的多孔涂层茎和皮质支柱同种异体移植物的严重股骨缺损的最低8年的调节后续血

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BACKGROUND:Revision total hip arthroplasty (THA) with severe femoral bone defects remains a major challenge. The purpose of this study is to report the minimum 8-year clinical and radiographic results of revision THA with severe femoral bone defects treated with extensively porous-coated stems and cortical strut allografts.METHODS:We retrospectively identified 44 patients diagnosed with Paprosky type III and IV femoral bone defects between January 2006 and July 2011. The exclusion criteria were patients not eligible for surgery, revised with extensively porous-coated stems alone, lost to follow-up and deceased. A total of 31 patients treated with extensively porous-coated stems and cortical strut allografts were finally included in this study. The degree of femoral bone defects was categorized as Paprosky type IIIA in 19 patients, type IIIB in 9 patients and type IV in 3 patients. The mean duration of follow-up was 11.0?±?1.5 (range, 8.1-13.5) years.RESULTS:The mean Harris Hip Score improved significantly from 43.4?±?10.5 points to 85.2?±?6.6 points (P??0.001). Similarly, WOMAC and SF-12 scores also significantly improved. Twenty-eight stems achieved stable bone ingrowth, two stems showed stable fibrous ingrowth, and one stem was radiologically unstable. Complete union and bridging between cortical strut allografts and host bone was achieved in all 31 patients. The femoral width was augmented with cortical strut allografts after revision surgery (an increase of 10.5?±?0.5?mm) and showed a slight decrease of 2.5?±?4.8?mm after the 10-year follow-up. Using re-revision for any reason as an endpoint, the Kaplan-Meier cumulative survival rate of the stem was 96.2% (95% confidence interval, 75.7-99.5%) at 10?years.CONCLUSION:Our data demonstrate that the use of extensively porous-coated stems combined with cortical strut allografts in revision THA with Paprosky type III and IV femoral bone defects can provide satisfactory clinical and radiographic outcomes with a minimum follow-up of 8?years.
机译:背景技术:重新修订严重股骨缺陷的总髋关节置换术(THA)仍然是一个重大挑战。本研究的目的是报告最低8年的临床和射线照相结果,其具有较大的股骨缺陷,用广泛的多孔涂层的茎和皮质支撑同种异体移植物。方法:我们回顾性地确定了44名患有乳头基III型患者的患者IV股骨骨缺陷于2006年1月至2011年7月。排斥标准是没有资格进行手术的患者,单独使用广泛的多孔涂层修订,失去随访和死亡。在本研究中,总共31例用广泛的多孔涂覆的茎和皮质支柱同种异体移植物治疗。股骨骨缺损程度被分类为19名患者的Paprosky IIIA,IIIB IIIB型,3例患者型IV型。随访的平均持续时间为11.0?±1.5(范围,8.1-13.5)多年。结果:平均哈里斯髋关节得分从43.4θ±10.5点到85.2?±6.6点(p?<? 0.001)。同样,Womac和SF-12分数也显着提高。二十八根茎达到稳定的骨骼向内,两个茎显示出稳定的纤维向内,并且一根茎在放射学不稳定。在所有31名患者中,在皮质支撑同种异体移植物和宿主骨之间完成​​联合和桥接。在修改手术后(增加10.5?±0.5Ωmm),用皮质支撑同种异体移植物增加股骨宽度,并在10年的随访后表现出略微减少2.5?±4.8?mm。使用重新修订的任何原因作为终点,茎的Kaplan-Meier累积存活率为10?多年的96.2%(95%置信区间,75.7-99.5%,75.7-99.5%)。结论:我们的数据表明广泛使用多孔涂覆的茎与皮质分子同种异体移植物联合皮疹III和IV股骨缺陷的修复THA可以提供令人满意的临床和射线照相结果,其中8岁的最低随访。

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