Novel alphavirus-based vaccine induces strong immune responses against prostate-specific antigen (PSA) and mediates tumor cell elimination in a mouse model of prostate cancer

Vladimir Ryabov; Peter Pushko; Irina Tretyakova; Rikka Saito; Richard B Alexander; Elena N Klyushnenkova

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Novel alphavirus-based vaccine induces strong immune responses against prostate-specific antigen (PSA) and mediates tumor cell elimination in a mouse model of prostate cancer

机译：基于新的alphavirus的疫苗诱导针对前列腺特异性抗原（PSA）的强烈免疫应答，并在前列腺癌的小鼠模型中介导肿瘤细胞消除

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来源
《Journal for ImmunoTherapy of Cancer 》 |2013年第s1期| 共页
作者
Vladimir Ryabov; Peter Pushko; Irina Tretyakova; Rikka Saito; Richard B Alexander; Elena N Klyushnenkova;
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中图分类肿瘤学 ;
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1. Anti-tumor effect of the alphavirus-based virus-like particle vector expressing prostate-specific antigen in a HLA-DR transgenic mouse model of prostate cancer [J] . Riabov V., Tretyakova I., Alexander R. B., Vaccine . 2015 ,第41期

机译：在前列腺癌的HLA-DR转基因小鼠模型中，表达基于前列腺病毒的抗原的基于alphavirus的病毒样颗粒载体的抗肿瘤作用
2. Antitumor immune response induced by DNA vaccine encoding human prostate-specific membrane antigen and mouse 4-1BBL. [J] . Kuang Y, Zhu H, Weng X, Urology . 2010 ,第2期

机译：由编码人前列腺特异性膜抗原和小鼠4-1BBL的DNA疫苗诱导的抗肿瘤免疫应答。
3. Vaccination with agonist peptide PSA: 154-163 (155L) derived from prostate specific antigen induced CD8 T-cell response to the native peptide PSA: 154-163 but failed to induce the reactivity against tumor targets expressing PSA: a phase 2 study in patients with recurrent prostate cancer. [J] . Kouiavskaia DV, Berard CA, Datena E Journal of immunotherapy . 2009 ,第6期

机译：源自前列腺特异性抗原的激动剂肽PSA：154-163（155L）的疫苗诱导对天然肽PSA：154-163的CD8 T细胞应答，但未能诱导针对表达PSA的肿瘤靶标的反应性：患者的2期研究与复发性前列腺癌。
4. Qualitative and quantitative investigation of glycans attached to Prostate-specific antigen (PSA) glycoprotein of healthy and cancer samples [C] . Ulrike Schweiger-Hufnagel, Kristina Marx, Wolfgang Jabs, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：对前列腺特异性抗原（PSA）糖蛋白对健康和癌症样品的定性和定量研究
5. Studies on human prostate-specific antigen as a tumor antigen for the immunotherapy of prostate cancer in a mouse model. [D] . Willis, Richard Allen. 2002

机译：人类前列腺特异性抗原作为一种肿瘤抗原的免疫模型在小鼠模型中的研究。
6. Novel alphavirus-based vaccine induces strong immune responses against prostate-specific antigen (PSA) and mediates tumor cell elimination in a mouse model of prostate cancer [O] . Vladimir Ryabov, Peter Pushko, Irina Tretyakova, 2013

机译：基于新型甲病毒的疫苗可诱导针对前列腺特异性抗原（PSA）的强烈免疫反应并介导前列腺癌小鼠模型中的肿瘤细胞消除
7. Novel alphavirus-based vaccine induces strong immune responses against prostate-specific antigen (PSA) and mediates tumor cell elimination in a mouse model of prostate cancer [O] . 2013

机译：基于新型甲病毒的疫苗可诱导针对前列腺特异性抗原（PSA）的强烈免疫反应，并介导前列腺癌小鼠模型中的肿瘤细胞消除

Novel alphavirus-based vaccine induces strong immune responses against prostate-specific antigen (PSA) and mediates tumor cell elimination in a mouse model of prostate cancer

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