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Clinical evaluation of silicone gel in the treatment of cleft lip scars

机译:硅胶治疗唇left裂的临床评价

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Upper lip scars are at risk of hypertrophy. Our center therefore uses microporous tape and silicone sheeting for postoperative scar care following cleft lip repair. However, some babies have previously ingested their silicone sheeting, which has the potential for respiratory compromise or gastrointestinal obstruction. Self-dry silicone gel is reportedly also effective for preventing hypertrophic scars. Hence, we sought to test whether silicone gel, which cannot be ingested whole, might be non-inferior to silicone sheeting for controlling against upper lip scar hypertrophy. This was a mixed prospective and retrospective case-controlled clinical trial involving patients undergoing unilateral cleft lip repair, 29 of whom received standard postoperative silicone sheeting (control group) and another 33 age-matched consecutive patients who received self-dry silicone instead. The Vancouver scar scale, visual analogue scale and photographically assessed scar width assessments were the same in both groups at six months after surgery. In conclusion, silicone gel appears to be non-inferior to silicone sheeting for postoperative care of upper lip scars as judged by scar quality at six months, but silicone sheeting has the safety disadvantage that it can be swallowed whole by babies. It is thus recommended that silicone gel be used for upper lip scar management in babies.
机译:上唇疤痕有肥大的危险。因此,我们的中心使用微孔胶带和硅胶布来修复唇裂后的术后疤痕。但是,某些婴儿先前已经摄入了硅胶片,这可能会导致呼吸道不适或胃肠道阻塞。据报道,自干硅凝胶也可有效预防增生性疤痕。因此,我们试图测试不能完全摄入的硅胶是否不劣于控制上唇疤痕肥大的硅胶片。这是一项混合的前瞻性和回顾性病例对照临床试验,涉及接受单侧唇裂修复的患者,其中29例接受标准术后硅胶片(对照组),另有33例年龄相匹配的连续患者改为使用自干硅胶。术后六个月,两组的温哥华疤痕量表,视觉模拟量表和照相评估的疤痕宽度评估结果相同。总之,根据六个月的疤痕质量判断,硅胶在上唇疤痕的术后护理方面似乎不逊于硅胶片,但是硅胶片的安全性缺点是可以被婴儿完全吞咽。因此,建议将硅胶用于婴儿的上唇疤痕处理。

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