Multidisciplinary Approach and Pivotal Role of Pathologist in Diagnosis of Breast Cancer: Technological Advances: An Updated Review for Breast Health Care experts

摘要

Clinical and pathological diagnosis of breast carcinoma is advancing at the same pace as the global increase in its incidence, morbidity and mortality. Research scientists (bio molecular, pathologists, clinicians and geneticists) are working on war footing for prevention, cure and treatment of breast cancer. In near future, breast cancer diagnosis may advance inexplicably.The pathology report serves not only as a hard copy for clinicians on which various treatment modalities are based , but also as a teaching module for educated cancer patients. The pathologist, who plays a very critical and pivotal role, hardly meets the patient in most institutional set ups. In unlimited resource centers, his/her role is very critical, because patients themselves can challenge clinicians and sue the pathologist.The scientific document based on observation can be finite, but the pathologist has to go beyond the finite observation, because many technical and clinical variations and limitations have to be taken into consideration. A guarded analytical opinion along with suggestions has to be given for the patient.Diagnosis of breast carcinoma has leaped rapidly from FNAC to DNA with many intermediaries in between. In some institutes, the best possible cost effective diagnosis is given, whereas in others, molecular studies are done to provide the diagnosis which influences the therapeutic and prognostic outlook.